Heart development: Mitochondria in command of cardiomyocyte differentiation

Drenckhahn J.

Research article (journal)

Abstract

Continuous developmental maturation of cardiomyocytes is essential to meet the functional and metabolic demands of the growing heart. A new study (Hom et al., 2011) reports that embryonic cardiomyocytes are influenced by mitochondrial maturation, such that closure of the mitochondrial permeability transition pore results in decreased levels of reactive oxygen species, thereby inducing differentiation. © 2011 Elsevier Inc.

Details about the publication

JournalDevelopmental Cell
Volume21
Issue3
Page range392-393
StatusPublished
Release year2011
Language in which the publication is writtenEnglish
DOI10.1016/j.devcel.2011.08.021
Link to the full texthttp://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=80052709722&origin=inward

Authors from the University of Münster

Drenckhahn, Jörg-Detlef
University Children's Hospital - Department for Paediatric Cardiology