Efficient Synthesis of Chiral 2,2'-Bipyrrolidines by an anti-Selective Alkene Diamination.

Müller CH, Fröhlich R, Daniliuc CG, Hennecke U

Research article (journal)

Abstract

The rapid and efficient construction of complex chiral bicyclic amines is possible using a novel alkene diamination reaction. Electrophilic iodinating agents promote the intramolecular anti-selective diamination of alkenes and allow the efficient synthesis of chiral amines such as trans-bipyrrolidines.

Details about the publication

JournalOrganic letters (Org Lett)
StatusPublished
Release year2012 (26/11/2012)
Language in which the publication is writtenUncoded languages
DOI10.1021/ol302855z

Authors from the University of Münster

Hennecke, Ulrich
Professur für Organische Chemie (Prof. Studer)