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The influence of G-quadruplex structure on DNA-based asymmetric catalysis using the G-quadruplex-bound cationic porphyrin TMPyP4·Cu.

Wilking M, Hennecke U

Research article (journal) | Peer reviewed

Abstract

The DNA G-quadruplex-binding porphyrin TMPyP4·Cu was found to form efficient hybrid catalysts for DNA-based asymmetric catalysis when bound to DNA G-quadruplexes. Nucleobase substitution experiments using human telomere-derived G-quadruplex sequences suggest binding of the porphyrin on the 3'-face.

Details about the publication

Journal: Organic and Biomolecular Chemistry (Org Biomol Chem)
Volume: 11
Issue: 40
Page range: 6940-5
Status: Published
Release year: 2013 (25/09/2013)
Language in which the publication is written: English
DOI: 10.1039/c3ob41366g

Authors from the University of Münster

Hennecke, Ulrich
Professur für Organische Chemie (Prof. Studer)

Projects the publication originates from

CRC 858 B08 - DNA as Chiral Element of Organisation for Catalysts in Aqueous Media (SFB 858)
Duration: 01/01/2010 - 31/12/2017 | 2nd Funding period
Funded by: DFG - Collaborative Research Centre
Type of project: Subproject in DFG-joint project hosted at University of Münster