The Risk of Colorectal Cancer in Patients with Ulcerative Colitis

Nowacki T., Brückner M., Eveslage M., Tepasse P., Pott F., Thoennissen N., Hengst K., Ross M., Bettenworth D.

Research article (journal) | Peer reviewed

Abstract

Conclusions: Despite the use of modern therapies for UC, CAC rates remain high. In our study, risk factors included disease duration while anti-inflammatory therapies reduced the risk. Effective control of the intestinal inflammation also reduced the disease burden as indicated by decreased risk of requiring colectomy, underscoring the need for sufficient surveillance and anti-inflammatory therapies.

Details about the publication

JournalDigestive Diseases and Sciences (Dig Dis Sci)
Volume60
Issue2
Page range492-501
StatusPublished
Release year2014
Language in which the publication is writtenEnglish
DOI10.1007/s10620-014-3373-2
Link to the full texthttp://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84921937791&origin=inward
KeywordsColitis-associated cancer (CAC); Colorectal cancer; Inflammatory bowel disease (IBD); Surveillance; Ulcerative colitis (UC)

Authors from the University of Münster

Bettenworth, Dominik
Medical Clinic of Internal Medicine B: Gastroenterology and Metabolic Disorders (Med B)
Brückner, Markus Georg
Medical Clinic of Internal Medicine B: Gastroenterology and Metabolic Disorders (Med B)
Eveslage, Maria
Institute of Biostatistics and Clinical Research (IBKF)
Nowacki, Tobias Max
Medical Clinic of Internal Medicine B: Gastroenterology and Metabolic Disorders (Med B)
Tepasse, Phil-Robin
Medical Clinic of Internal Medicine B: Gastroenterology and Metabolic Disorders (Med B)