Therapeutic approaches in adults with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): A review of current evidence.

Stögbauer J; Schegerer V; Klein C; Pawlitzki M; Meuth SG; Aktas O; Groppa S; Fousse M

Review article (journal) | Peer reviewed

Abstract

Recent years have seen a considerable increase in knowledge pertaining to Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD). Nevertheless, a noteworthy degree of uncertainty remains within the neurological community, primarily due to the often highly heterogeneous nature of the disease and the absence of approved long-term treatment options. In this article, we undertake a comprehensive review of the various treatment strategies and drug options available for the pharmacological treatment of acute attacks and relapses in MOGAD.

Details about the publication

JournalAutoimmunity Reviews (Autoimmun Rev)
Volume25
Issue2
Page range103970-103970
Statusaccepted / in press (not yet published)
Release year2026 (28/02/2026)
Language in which the publication is writtenEnglish
DOI10.1016/j.autrev.2025.103970
Link to the full texthttps://www.sciencedirect.com/science/article/pii/S1568997225002319?via%3Dihub
KeywordsHumans; Myelin-Oligodendrocyte Glycoprotein; Autoantibodies; Adult; Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

Authors from the University of Münster

Meuth, Sven
Department for Neurology