Programmierung der DNA-Methylierungsmuster in der männlichen Keimbahn
Laurentino, Sandra; Neuhaus, Nina
Review article (journal)Abstract
DNA methylation is essential for cell identity and integrity. The genome of the mammalian germline undergoes two waves of genome-wide methylation reprogramming during embryonic development. Recent data revealed that the male germline in the adult is also continuously reprogrammed at each spermatogenic cycle, revealing windows of opportunity for lifelong impact on the paternal epigenome, potentially affecting fertility and the integrity of paternal non-genetic information.
Details about the publication
Journal: BIOspektrum
Volume: 31
Issue: 2
Page range: 170-172
Status: Published
Release year: 2025
Language in which the publication is written: German
Link to the full text: https://link.springer.com/article/10.1007/s12268-025-2446-4
Keywords: DNA-Methylierung; Keimzellen; Männliche Infertilität
Authors from the University of Münster
| Laurentino, Sandra | Institute of Reproductive Genetics |
| Neuhaus, Nina Julia | Institut für Reproduktions- und Regenerationsbiologie |