Characterization of endometrial mesenchymal stem-like cells obtained by endometrial biopsy during routine diagnostics.
Schüring AN, Schulte N, Kelsch R, Röpke A, Kiesel L, Götte M
Research article (journal)Abstract
Endometrial cell clones derived from in vitro cultured purified stromal cells obtained by endometrial biopsy display characteristic stem cell features, including clonality; long-term culturing properties; multilineage differentiation potential; expression of CD146, CD105, CD90, CD73, MSI1, NOTCH1, and SOX2; and absence of CD34 and CD14 expression. We conclude that adult stem cells are present in endometrial biopsies performed in a routine clinical setting, offering new large-scale approaches for future research, diagnostics, and therapies involving adult stem cells.
Details about the publication
Journal: Fertility and Sterility (Fertil Steril)
Volume: 95
Issue: 1
Page range: 423-426
Status: Published
Release year: 2011
Language in which the publication is written: English
Authors from the University of Münster
| Götte, Martin | |
| Kelsch, Reinhard | |
| Kiesel, Ludwig | |
| Röpke, Albrecht |
Distinctions received for the publication
| Prize of the German Menopause Society Awarded by: German Menopause Society Award given to: Götte, Martin Announced at: 15/11/2010 | Date of awarding: 15/11/2010 Type of distinction: Best presentation award |