Kidney-autotransplantation before radiotherapy: a case report.

Bölling T, Janke K, Wolters HH, Glashörster M, Ernst I, Willich N, Brockmann J, Könemann S

Research article (journal)

Abstract

BACKGROUND: A 28-year-old man suffering from a Ewing tumour arising from the 9th-11th ribs with infiltration of neuroforamina without distant metastases was planned to receive radiotherapy following primary intralesional surgery and induction chemotherapy. Due to pleural infiltration and effusion, a hemithorax irradiation with a sequential boost to the primary tumour site had to be administered. Different treatment planning variants failed to provide sufficient radiotherapy planning in view of target volume coverage and avoidance of organs at risk, especially due to high calculated radiation doses potentially compromising the left kidney. MATERIALS AND METHODS: To prevent left kidney organ exposure, an autotransplantation of the left kidney into the right fossa iliaca was performed. An infiltration of the kidney was initially excluded. RESULTS: Postoperatively, a renal scintigraphy showed a normal function of both kidneys allowing sufficient radiotherapy treatment planning. Target volume coverage was easily obtained using a combination of hemithorax irradiation and a sequential boost by an intensity-modulated-radiotherapy technique. CONCLUSION: In difficult individual treatment situations, surgical transpositions as well as organ autotransplantation might be useful in reducing radiotherapy organ dose levels.

Details about the publication

JournalAnticancer Research (Anticancer Res)
Volume29
Issue8
Page range3397-3400
StatusPublished
Release year2009
Language in which the publication is writtenEnglish
KeywordsMagnetic Resonance Imaging; Sarcoma Ewing's; Humans; Male; Radiotherapy Planning Computer-Assisted; Transplantation Autologous; Bone Neoplasms; Radiotherapy Dosage; Adult; Kidney; Radiotherapy Intensity-Modulated; Kidney Transplantation; Magnetic Resonance Imaging; Sarcoma Ewing's; Humans; Male; Radiotherapy Planning Computer-Assisted; Transplantation Autologous; Bone Neoplasms; Radiotherapy Dosage; Adult; Kidney; Radiotherapy Intensity-Modulated; Kidney Transplantation

Authors from the University of Münster

Bölling, Tobias
Clinic for Radiotherapy
Ernst, Iris
Clinic for Radiotherapy
Janke, Kirsten
Clinic of Radiology
Willich, Normann
Clinic for Radiotherapy
Wolters, Heiner
General Surgery Clinic