Atypical ductal hyperplasia and atypical epithelial proliferation of ductal type

Böcker W, Hungermann D, Weigel S, Roterberg K, Decker T

Research article (journal)

Abstract

The definition of atypical ductal hyperplasia (ADH) encompasses qualitative and quantitative criteria. Qualitative criteria include cytological and architectural features similar to those of low grade ductal carcinoma in situ (DCIS), the quantitative criteria are characterized by metric features (2 mm or 2 ductules) or by the confines of lobules. In this article we discuss the morphology of ADH, the status of ADH in the low grade pathway of breast carcinoma development and its clinical significance. Furthermore, we comment some special forms of atypical epithelial proliferations of the ductal type.

Details about the publication

JournalDer Pathologe
Volume30
Issue1
Page range42-48
StatusPublished
Release year2009
Language in which the publication is writtenGerman
KeywordsEpithelial Cells; Loss of Heterozygosity; Carcinoma in Situ; Female; Hyperplasia; Breast Neoplasms; Humans; Biopsy; Carcinoma Ductal Breast; Keratins; Cell Division; Epithelial Cells; Loss of Heterozygosity; Carcinoma in Situ; Female; Hyperplasia; Breast Neoplasms; Humans; Biopsy; Carcinoma Ductal Breast; Keratins; Cell Division

Authors from the University of Münster

Hungermann, Daniela
Gerhard Domagk Institute of Pathology
Weigel, Stefanie Bettina
Clinic of Radiology