CRC 858 A02 - Compounds consisting of Group 13 Lewis Acids and Nitrogen containing Lewis Bases for Bifunctional Activation (SFB 858)

Basic data for this project

Description

The project investigates the synthesis and reactivity of bi-functional compounds featuring Lewis acidic (unsaturated three coordinate aluminum or gallium atoms) and Lewis basic (nitrogen atoms) functionalities in the same molecule. Self-quenching of the opposite functionalities as a result of inter- or intramolecular adduct formation is to be suppressed completely or at least limited to only weak by the introduction of sterically demanding ligands and/or spacer units. Such carefully designed donor- and acceptor groups are expected to activate σ- and or π-bonds of suitable substrates in a cooperative manner. Hereby we will influence the reactivity and selectivity of small molecules in specific functionalisations and reactions such as cycloadditions or the synthesis of heterocycles in a rational way.