CRC 858 B03 - Organisation of lipophilized Biomolecules at Surfaces: Chemistry and Patterning (SFB 858)

Basic data for this project

Description

The major goal of project B3 is to cover surfaces with structured, self assembled and functionalized molecular layers in order to study patterning and selective chemical reactions on these two dimensional systems. For this purpose, a collection of lipophilzed biogenic molecules will be applied, which enables the generation of intermolecular hydrogen bonds: with e.g. their pendant molecules, with similar compounds (namely nucleobases A, T, C and G), with carbohydrates. Also a combination of these compounds equipped with long alkyl chains shall be tested. Patterning then can be the result of cooperative interactions on solid surfaces. Furthermore, the architecture of complex supramolecular pattern shall be performed through the synthesis of specific non-linear building blocks. We want to analyze the influence of cooperative effects along these patterning processes by systematic variation of external parameters. Also potential kinetic parameters in combination with effects resulting from non-equilibrium states will be analyzed. Additionally, we want to explore conditions that allow performing specific reactions at the surface like the generation of metal complexes, of adducts , of surface bond catalysts and the stabilization of unusual polymer architectures. Theoretical analyses like Monte-Carlo-simulations support the experimental studies: Which cooperative alignment of two alkyl chains induces the overall patterning? How do defects decrease cooperative effects? The corresponding free energies shall be calculated by determination of the energetic and entropic contribution terms and thus enable the prediction and/or explanation of temperature dependencies.CRC 858 B03 - Organisation of lipophilized Biomolecules at Surfaces: Chemistry and Patterning (Chi, Heuer, Erker)