CRC C12 - The Role of Circulating Monocytes in the Post-Ischaemic Myocardium

Basic data for this project

Type of project: Subproject in DFG-joint project hosted at University of Münster

Duration at the University of Münster: 01/07/2013 - 30/06/2017 | 1st Funding period

Description

Monocytes are a therapeutic target after acute myocardial infarction, because they contribute to i) reperfusion injury (hours after reperfusion), and ii) repair (days - weeks after reperfusion). There is no data available concerning the (transient) accumulation of monocytes or monocyte subsets in the myocardium following (reperfused) acute myocardial infarctions. Imaging of monocytes will allow the detection of these cells in the heart and their association with either the infarct zone or border zone and the remote myocardium. We aim to investigate the localisation of mononuclear cell types in the post-ischaemic myocardium and their contribution to post-infarct healing using imaging.

Keywords: myocardium

Website of the project: http://www.uni-muenster.de/Sfbmobil/projekte/organfunktion/c12.php

Funding identifier: SFB656/32013

Funder / funding scheme:

DFG - Collaborative Research Centre (SFB)

Project management at the University of Münster

Waltenberger, Johannes Ludwig

Department for Cardiovascular Medicine

Applicants from the University of Münster