CRC TRR 332 - B05: Innate immune memory of neutrophils during inflammation

Basic data for this project

Type of project: Subproject in DFG-joint project hosted at University of Münster

Duration at the University of Münster: 01/07/2022 - 30/06/2026 | 1st Funding period

Description

Molecular pathways underlying neutrophil diversity remain ill-defined. In this project we will follow the hypothesis that mechanisms of innate immune memory prime the functional phenotype of neutrophils regarding their subsequent response patterns; a process which may be relevant during development of myeloid stem cells as well as during repetitive stimulation of mature (sub)-populations of neutrophils. The long-term goal of our project is the targeted manipulation of innate immune memory mechanisms in neutrophils for treatment of inflammatory diseases.

Keywords: Neutrophile; Immunologie

Website of the project: https://www.medizin.uni-muenster.de/sfb-trr-332/forschung/project-area-b.html

DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/505387110

Funding identifier: TRR 332/1, B05 | DFG project number: 449437943

Funder / funding scheme: