CRC 1348 B07 - Morphogenetic mechanisms during lymphatic vessel formation
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2018 - 31/12/2021 | 1st Funding period
Description
This proposal wants to understand the molecular mechanisms acting at the membrane / extracellular matrix interface of migrating lymphatic endothelial cells, directing their morphogenetic behaviour. For this, we will visualize migrating lymphatic endothelial progenitor cells (LEPCs) in the mouse fetus and determine the expression patterns of CCBE1, VEGF-C and uPAR in relation to LEPC migration. The generation of in vitro models for the migration of LEPCs will allow further analysis of various aspects of this process.
Keywords: VEGF-C; VE-Cadherin; Lymphendothel
Website of the project: http://sfb1348.uni-muenster.de
Funding identifier: SFB 1348/1 B07
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Kiefer, Friedemann | European Institute of Molecular Imaging (EIMI) |
Applicants from the University of Münster
| Kiefer, Friedemann | European Institute of Molecular Imaging (EIMI) |