CRC 1348 A06 - Force-control in neurons via curved membrane nanodomains

Basic data for this project

Type of projectSubproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster01/01/2018 - 31/12/2021 | 1st Funding period

Description

The project studies receptor-independent signaling platforms, where mechanical forces at the PM are translated into classical biochemical signal transduction cascades via nanoscale membrane deformations. This type of mechano-chemical signal translation at cellular membranes relies on recruitment of curvature-sensitive signaling molecules. Here we aim to investigate how transiently forming curved PM nanodomains regulate actin-based forces in developing mouse neurons.

KeywordsNanodomäne; Aktin; Neuron
Website of the projecthttp://sfb1348.uni-muenster.de/
Funding identifierSFB 1348/1 A06
Funder / funding scheme
  • DFG - Collaborative Research Centre (SFB)

Project management at the University of Münster

Galic, Milos
Institute of Medical Physics and Biophysics

Applicants from the University of Münster

Galic, Milos
Institute of Medical Physics and Biophysics