CRC 1348 A04 - Membrane platforms in regulated secretion from endothelial cells

Basic data for this project

Type of projectSubproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster01/01/2018 - 31/12/2021 | 1st Funding period

Description

This project addresses how membrane platforms rich in PA and PI(4,5)P2 serve as Weibel-Palade body (WPB) tethering and/or fusion sites, which proteins are required to establish these platforms and how they link to the WPB. In particular, we analyze the contribution of different Rab proteins and Rab effector functions in the late steps of WPB exocytosis.

KeywordsEndothel; Rab Proteine
Website of the projecthttp://sfb1348.uni-muenster.de/
Funding identifierSFB 1348/1 A04
Funder / funding scheme
  • DFG - Collaborative Research Centre (SFB)

Project management at the University of Münster

Gerke, Volker
Institute of Medical Biochemistry

Applicants from the University of Münster

Gerke, Volker
Institute of Medical Biochemistry