Mikrobielle Biofabriken: PolyMore - Ein Paenibacillus-Polymyxa-Chassis für die chemische Produktion und neue Sporenprozesse (Teilprojekt A) (PolyMore)

Basic data for this project

Type of project: Participation in BMBF-joint project

Duration at the University of Münster: 01/09/2021 - 31/12/2023 (Initial start date: 01/02/2020)

Description

Aim of the project is the development of a novel Paenibacillus polymyxachassis organism for application in biorefinery principles. Based on an already existing tailored CRISPR-Cas9 system this strain will be further developed towards a robust and reliable production host which is perfectly adapted towards the utilization of renewable resources. The genus Paenibacillus is perfectly suited for biorefinery processes by its broad substrate spectra as well as lignin metabolization and manifold antimicrobial activity as well as natural tolerance against inhibitory compounds resulting from lignocellulose-based pretreatments. Within PolyMore we strive for the junction of all benefits from the various Paenibacilli strains in a single highly robust chassis. By use of a holistic systems biology approach we will perform an in-depth characterization which will guide the further optimization.

Keywords: Mikrobiologie; Biofabrik; Bioökonomie; Plattformorganismus

Funding identifier: 031B0855A

Funder / funding scheme:

Federal Ministry of Education and Research (BMBF)

Project management at the University of Münster

Schmid, Jochen

Institute of Molecular Microbiology and Biotechnology

Applicants from the University of Münster