CRC 1450 C07 - Imaging of immune cell dynamics and host-pathogen interactions in gut-associated lymphoid tissue during Yersinia pseudotuberculosis infections
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2021 - 31/12/2024 | 1st Funding period
Description
In order to obtain a high spatio-temporal resolution of the infection process of the gut pathogen Yersinia pseudotuberculosis, we will image the recruitment and dynamics of immune cell populations and characterize Yersinia-targeted immune cells in infected lymphoid tissue of mice during the entire course of the infection. In this context, we will also analyse the role of platelets for neutrophil recruitment and address different neutrophil functions, including NET formation, and how they are manipulated by bacterial evasion mechanisms.
Keywords: Yersinia pseudotuberculosis; Infektion; Immunologie; Darmbakterien
Website of the project: https://www.uni-muenster.de/CRC-inSight/research/area-C/C07.php
Funding identifier: SFB 1450/1, C07
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Dersch, Petra | Institute of Infectiology |
| Rossaint, Jan Peter | Clinic for Anaesthesiology, Surgical Critical Care Medicine and Pain Therapy |
Applicants from the University of Münster
| Dersch, Petra | Institute of Infectiology |
| Rossaint, Jan Peter | Clinic for Anaesthesiology, Surgical Critical Care Medicine and Pain Therapy |