CRC 1450 - C07: Imaging of immune cell dynamics and host-pathogen interactions in gut-associated lymphoid tissue during Yersinia pseudotuberculosis infections
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2021 - 31/12/2024 | 1st Funding period
Description
In order to obtain a high spatio-temporal resolution of the infection process of the gut pathogen Yersinia pseudotuberculosis, we will image the recruitment and dynamics of immune cell populations and characterize Yersinia-targeted immune cells in infected lymphoid tissue of mice during the entire course of the infection. In this context, we will also analyse the role of platelets for neutrophil recruitment and address different neutrophil functions, including NET formation, and how they are manipulated by bacterial evasion mechanisms.
Keywords: Yersinia pseudotuberculosis; Infektion; Immunologie; Darmbakterien
Website of the project: https://www.uni-muenster.de/CRC-inSight/research/area-C/C07.php
DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/452347294
Funding identifier: SFB 1450/1, C07 | DFG project number: 431460824
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Dersch, Petra | |
| Rossaint, Jan Peter |
Applicants from the University of Münster
| Dersch, Petra | |
| Rossaint, Jan Peter |
Projects of the following funding period
Duration: 01/01/2025 - 31/12/2028 | 2nd Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster |
Related main project
Duration: 01/01/2021 - 31/12/2024 | 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Main DFG-project hosted at University of Münster |