CRC 1450 - B02: Quantitative MRI of organ-specific vascular permeability and immune cell dynamics by combination with mass spectrometric imaging
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2021 - 31/12/2024 | 1st Funding period
Description
The aim of this project is to develop combined in vivo MRI and ex vivo mass spectrometry imaging (MSI) methods including both, laser ablation-inductively coupled plasma-mass spectrometry imaging (LA-ICP-MSI) and matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI). MSI shall be used to develop fully quantitative MRI methods as part of our comprehensive multiscale imaging strategy to analyse immune responses in disease models and patients in vivo. The overarching question is how quantitative MR parameters depend on elemental and molecular patterns in tissues, and how this dependence evolves during inflammatory responses.
Keywords: MRI; mass spectrometry; Radiology; Nuclear Medicine; Radiotherapy; Radiobiology
Website of the project: https://www.uni-muenster.de/CRC-inSight/research/area-B/B02.php
Funding identifier: SFB 1450/1, B02
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Faber, Cornelius Joachim | Clinic of Radiology |
| Karst, Uwe | Professur für Analytische Chemie (Prof. Karst) |
Applicants from the University of Münster
| Faber, Cornelius Joachim | Clinic of Radiology |
| Karst, Uwe | Professur für Analytische Chemie (Prof. Karst) |