CRC 1450 A05 - Targeting immune cell dynamics by longitudinal whole-body imaging and mathematical modelling
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2021 - 31/12/2024 | 1st Funding period
Description
We develop strategies for tracking and quantifying (immune) cell populations or even single cells in long-term (days) whole-body PET studies in mice and humans. This will be achieved through novel acquisition protocols, measured and simulated phantom data, use of prior information from MRI and microscopy, mathematical modelling, and mathematical analysis of image reconstruction with novel regularization paradigms based on optimal transport. Particular applications include imaging and tracking of macrophages and neutrophils following myocardial ischemia-reperfusion or in arthritis and sepsis.
Keywords: Medical imaging; Cell dynamics; Biomedical Technology; Medical Physics; Analysis; Numerics
Website of the project: https://www.uni-muenster.de/CRC-inSight/research/area-A/A05.php
Funding identifier: SFB 1450/1, A05
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Schäfers, Klaus | European Institute of Molecular Imaging (EIMI) |
| Wirth, Benedikt | Professorship of Biomedical Computing/Modelling (Prof. Wirth) |
Applicants from the University of Münster
| Schäfers, Klaus | European Institute of Molecular Imaging (EIMI) |
| Wirth, Benedikt | Professorship of Biomedical Computing/Modelling (Prof. Wirth) |