CRC 1450: Multiscale Imaging of Organ-Specific Inflammation (inSight)

Basic data for this project

Description

Inflammation can heal but it can also be destructive, for example in chronic cases. The Collaborative Research Centre "Multiscale Imaging of Organ-Specific Inflammation" will examine the organ-specific regulation of inflammation, particularly with regard to the dynamics, activity and interactions of inflammatory cells in various organs. In particular, the leukocytes involved in inflammation, their transfer from the blood to the tissue, the sequence of their activation at the site of the inflammation and their contribution to tissue damage in the living organism are to be analysed. The methods used should make it possible to track cells and processes using whole-body imaging, among other things, and thus to collect new data across spatial and temporal scales for a better understanding of inflammation.