CRC 1348 - B10: Spatiotemporal regulation of secretory lysosome trafficking controls epithelial tube fusion

Basic data for this project

Type of project: Subproject in DFG-joint project hosted at University of Münster

Duration at the University of Münster: 01/01/2018 - 31/12/2021 | 1st Funding period

Description

This proposal investigates the mechanism of luminal plasma membrane fusion using a combination of genetic, live imaging, and biophysical approaches. We will focus on the role of secretory lysosomes (SLs), in particular addressing how they deliver membrane material to specific cellular interfaces in tracheal fusion cells. We will investigate the formation, the dynamic behavior, and the regulation of SLs by Ca2+ signaling.

Keywords: Biologie; Neurobiologie; Verhaltensbiologie

Website of the project: http://sfb1348.uni-muenster.de

DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/394435061

Funding identifier: SFB 1348/1 B10 | DFG project number: 386797833

Funder / funding scheme: