CRC 1348 - A13: Lipid storage organelles in formation of polarized cellular interfaces during cell division and cell fusion

Basic data for this project

Type of project: Subproject in DFG-joint project hosted at University of Münster

Duration at the University of Münster: 01/01/2026 - 31/12/2029 | 2nd Funding period

Description

Lipid droplets (LDs), ubiquitous organelles for lipid storage, establish direct contact with the plasma membrane (PM), but the mechanistic basis of this interaction and its role in PM remodeling are largely unexplored. We have identified the machinery driving the acto-myosin dependent transport of LDs to polarized PM domains. We will build on these findings to uncover the molecular components and biological roles of LD-PM contact sites, and the implications of these structures for cellular adaptability.

Keywords: Zellpolarität

Website of the project: https://www.uni-muenster.de/SFB1348/en/projects/PROJECT_A13.html

DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/496760577

Funding identifier: SFB 1348/3, A13 | DFG project number: 386797833

Funder / funding scheme: