CRC 1450 - B07: Targeting plexin signalling and its role in immune modulation
Basic data for this project
Type of project: Subproject in DFG-joint project hosted at University of Münster
Duration at the University of Münster: 01/01/2025 - 31/12/2028 | 1st Funding period
Description
We aim to develop innovative approaches to investigate the membrane organization, activation, and signalling mechanism of undervalued key molecules in innate immunity, semaphorin ligands and plexin receptors. Within this CRC, my group will use advanced multiscale imaging to spatiotemporally investigate how semaphorins modulate cancer cell migration processes in 2D and 3D environments. Cell-cell interactions for a diverse set of immune cells, interacting with cancerous cells will provide novel insights into the role of these molecules in immune modulation.
Keywords: Angeborene Immunantwort; Semaphorin; Plexinrezeptor
Website of the project: https://www.uni-muenster.de/CRC-inSight/research/area-B/B07.php
DFG-Gepris-ID: https://gepris.dfg.de/gepris/projekt/549339951
Funding identifier: SFB 1450/2, B07 | DFG project number: 431460824
Funder / funding scheme:
- DFG - Collaborative Research Centre (SFB)
Project management at the University of Münster
| Sánchez, Maria Florencia | European Institute of Molecular Imaging (EIMI) |
Applicants from the University of Münster
| Sánchez, Maria Florencia | European Institute of Molecular Imaging (EIMI) |