CRC 1459 - B04: Multistimuli sensing with memory and feedback function using photoswitchable proteins

Basic data for this project

Description

Our goal is to harness a molecular toolbox of different light-responsive proteins and their photoactivation with in situ generated light for integrating these proteins into reaction networks, creating systems that demonstrate adaptive and pulsatile responses. As demonstrators, we plan to incorporate the photoswitchable proteins into diverse soft material systems including protein aggregates, supported lipid bilayers and giant unilamellar vesicles. The project will revolve around reaction networks with light responsive elements that can be fueled externally as well as in situ by chemiluminescence and bioluminescence reactions. Moreover, we aim to produce systems with transient pulsatile responses to changes in illumination.