Dr. rer. nat. Linda Brunotte

Current affiliations

Institute of Molecular Virology

Publications

Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier. Faist A; Schloer S; Mecate-Zambrano A; Janowski J; Schreiber A; Boergeling Y; Conrad BCG; Kumar S; Toebben L; Schughart K; Baumgardt M; Kessler M; Hoenzke K; Hocke A; Trautmann M; Kato H; Hartmann W; Christersson A; Rescher U; Mellmann A; Kuehn J; Kuempers P; Wolff T; Wiewrodt R; Rovas A; Barth P; Wiebe K; Brunotte L; Ludwig S (2023) In: Antiviral Research, 209 Type of Publication: Research article (journal)
The ubiquitination landscape of the influenza A virus polymerase Günl F.; Krischuns T.; Schreiber J.A.; Henschel L.; Wahrenburg M.; Drexler H.C.A.; Leidel S.A.; Cojocaru V.; Seebohm G.; Mellmann A.; Schwemmle M.; Ludwig S.; Brunotte L.; (2023) In: Nature Communications, 14(1) Type of Publication: Research article (journal)
Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants. Ferrando VA; Friedrich ME; Gandhi S; Mellmann A; Masemann D; Christersson A; Anhlan D; Brunotte L; Stoll M; Harder T; Beer M; Boergeling Y; Ludwig S (2023) In: Emerging Microbes and Infections, 12(1) Type of Publication: Research article (journal)
Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA. Kleinehr J; Schöfbänker M; Daniel K; Günl F; Mohamed FF; Janowski J; Brunotte L; Boergeling Y; Liebmann M; Behrens M; Gerdemann A; Klotz L; Esselen M; Humpf HU; Ludwig S; Hrincius ER (2023) In: PLoS Pathogens, 19(7) Type of Publication: Research article (journal)
The annexin A1/FPR2 signaling axis expands alveolar macrophages, limits viral replication, and attenuates pathogenesis in the murine influenza A virus infection model Schloer, S; Hübel, N; Masemann, D; Pajonczyk, D; Brunotte, L; Ehrhardt, C; Brandenburg, LO; Ludwig, S; Gerke, V; Rescher, U (2019) In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 33(11) Type of Publication: Research article (journal)

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Projects

KFO 342 - P6: Disease Tailored Therapeutic Strategies against Hyperinflammatory Viral Infections caused by Highly Pathogenic Respiratory Viruses Duration: 01/10/2023 - 30/09/2026 \| 2nd Funding period Funded by: DFG - Clinical Research Unit Type of project: Subproject in DFG-joint project hosted at University of Münster
KFO 342 - P6: Exploring the mechanisms of cytokine storm induction and systemic infection by highly pathogenic influenza viruses Duration: 01/10/2019 - 30/09/2023 \| 1st Funding period Funded by: DFG - Clinical Research Unit Type of project: Subproject in DFG-joint project hosted at University of Münster

Prizes

Travel Awards für Fachkonferenzen
Awarded by: Cells in Motion Interfaculty Centre
Award given to: Brunotte, Linda
Announced at: 01/01/2020
Type of distinction: Scholarship