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Prof. Dr. Melanie Esselen

Current affiliations

Professorship for food chemistry (Prof. Esselen)

Curriculum Vitae (CV)

Gentoxische Pflanzeninhaltsstoffe (Testsysteme: Mikrokern-Test, Comet Assay, HPRT-Test)
Zellkulturstudien - Toxizität und Metabolismus
Post-translationale Proteinmodifikationen durch sekundäre Pflanzenstoffe
Bioanalytik (ELISA, Durchflusszytometrie, Western Blot, RealTime PCR, Fluoreszenzmikroskopie)

Functions and Memberships
since 2013	Gesellschaft Umwelt-Mutationsforschung e.V.
since 2012	Gesellschaft Deutscher Chemiker (GDCh) e.V. Lebensmittelchemische Gesellschaft (LChG)
since 2007	Deutsche Gesellschaft für Pharmakologie und Toxikologie (GT)

Publications

Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats Hassan, R.; Gerdemann, A.; Cramer, B.; Hobloss, Z.; Myllys, M.; González, D.; Albrecht, W.; Veerkamp, J.; Friebel, A.; Hoehme, S.; Esselen, M.; Degen, G.; Humpf, H.; Hengstler, J.; Ghallab, A. (2024) In: Archives of Toxicology, 98(4) Type of Publication: Research article (journal)
P13-16 Studies on the toxicology of electrolyte additives – mechanisms and changes during cycling Muschiol, Elisabeth; Tölke Louisa; Lechtenfeld, Christian; Nowak, Sascha; Esselen, Melanie (2024) In: Toxicology Letters, 399(2) Type of Publication: Research article (journal)
Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS Gerdemann, A; Cramer, B; Degen, G H; Veerkamp, J; Günther, G; Albrecht, W; Behrens, M; Esselen, M; Ghallab, A; Hengstler, J G; Humpf, H-U (2023) In: Archives of Toxicology, 97(12) Type of Publication: Research article (journal)
Polyphenols Cause Structure Dependent Effects on the Metabolic Profile of Human Hepatocarcinogenic Cells. Gerdemann A; Broenhorst M; Behrens M; Humpf HU; Esselen M (2023) In: Molecular Nutrition and Food Research, 67(21) Type of Publication: Research article (journal)
Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA. Kleinehr J; Schöfbänker M; Daniel K; Günl F; Mohamed FF; Janowski J; Brunotte L; Boergeling Y; Liebmann M; Behrens M; Gerdemann A; Klotz L; Esselen M; Humpf HU; Ludwig S; Hrincius ER (2023) In: PLoS Pathogens, 19(7) Type of Publication: Research article (journal)

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Projects

International Graduate School of Battery Chemistry, Characterization, Analysis, Recycling and Application (BACCARA) Duration: 01/07/2020 - 31/12/2027 Funded by: Federal Ministry of Culture and Science of the Federal State of North Rhine-Westphalia, PowerCo SE Type of project: Individual project
Metabolism and genotoxicity of carcinogenic phenylpropanoids naturally occuring in food Duration: 16/01/2015 - 31/03/2017 Funded by: DFG - Individual Grants Programme Type of project: Individual project
Förderung der Regelprofessur im Fach "Lebensmittelchemie" im Rahmen des Professorinnenprogramms II an der Westfälischen Wilhelms-Universität Münster Duration: 01/10/2014 - 30/09/2019 Funded by: Federal Ministry of Education and Research Type of project: Individual project
Extraction, identification of Maillard reaction products in Chinese traditional foodstuffs and their cellular effects on human cell lines Duration: 01/08/2012 - 31/07/2015 Type of project: Own resources project

Talks

Bioaktiv oder gentoxisch -Beeinflussung der DNA-Integrität durch Arzneipflanzen- und Lebensmittelinhaltsstoffe Esselen, Melanie (21/09/2019) Phytotherapiekongress, Münster Type of talk: scientific talk
DNA-Reparatur als zelluläre Antwort auf gentoxische sekundäre Pflanzenstoffe Lena Hermes, Melanie Esselen (13/03/2019) Arbeitstagung des Reginoalverbandes Nordrhein-Westfalen (LChG), Wuppertal Type of talk: scientific talk
Komplexe molekulare Mechanismen von gentoxischen Phenylpropanoiden Esselen, Melanie (17/09/2018) 47. Deutschen Lebensmittelchemikertag , Berlin Type of talk: scientific talk
Round Table Discussion on Career Development Esselen, Melanie; Haase, Andrea; Krüger, Christopher; Piberger, Ann Liza (09/09/2018) 15th Biennial Meeting of the DGDR - DNA Repair, Karlsruhe Type of talk: practical talk
Einfluss des Grünteepolyphenols (-)-Epigallocatechin-3-Gallat auf Histondeacetylasen in der humanen Kolonkarzinomzellen Pöppelmann, Tobias; Feuls, Jana; Esselen, Melanie (14/03/2018) LChG-Regionalverband NRW Arbeitstagung 2018, Essen Type of talk: scientific talk

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Prizes

"Goldener Brendel" für die Vorlesung "Lebensmittelchemie und -technologie II" Awarded by: Fachschaft Chemie Award given to: Esselen, Melanie Announced at: 01/01/2017 \| Date of awarding: 01/01/2017 Type of distinction: Research award or other distinction
Kurt-Täufel-Preis des Jungen Lebensmittelchemikers Awarded by: Gesellschaft Deutscher Chemiker e.V. (GDCh) Award given to: Esselen, Melanie Announced at: 01/01/2013 \| Date of awarding: 01/01/2013 Type of distinction: Research award or other distinction

Doctorates

Impact of polyphenols on post translational modifications of Sumo-1 target proteins Candidate: Pöppelmann, Tobias \| Supervisors: Esselen, Melanie; Humpf, Hans-Ulrich Period of time: 15/11/2015 - 31/12/2018 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Cellular mechanism of not enzymatic oxidation products of poly unsaturated fatty acids. Candidate: Zielinski, Alexa \| Supervisors: Esselen, Melanie; Humpf, Hans-Ulrich Period of time: 01/09/2015 - 31/08/2018 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Penicillium spp. as a Source of Secondary Metabolites: Structure Elucidation, Occurrence in Food, Cytotoxicity, and Biological Activity Candidate: Kalinina Svetlana \| Supervisors: Humpf, Hans-Ulrich Period of time: 01/10/2014 - 27/07/2018 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Impact of phenyl propanoids on cellular redox status. Candidate: Uebel, Thomas \| Supervisors: Esselen, Melanie; Humpf, Hans-Ulrich Period of time: 15/11/2014 - 30/04/2018 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Endokrine Fibroblasten-Wachstumsfaktoren als Regulatoren der beta-Zellfunktion und beta-Zellviabilität Candidate: Pajaziti, Betina \| Supervisors: Düfer, Martina; Hempel, Georg; Esselen, Melanie Period of time: until 26/01/2018 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

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