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Apl. Professor Dr.rer.nat. Georg Hempel

Current affiliations

Professur für Klinische Pharmazie (Prof. Hempel) (apl.)

Curriculum Vitae (CV)

Therapieoptmierung in der Pädiatrischen Onkologie
Pharmakokinetik und Pharmakokinetik / -dynamik Modelling
Pharmazeutische Betreuung in der Geriatrie
Bioanalytik von Arzneistoffen in biologischen Flüssigkeiten

Academic Education
07/1991 - 03/1995	Promotion
Work Experience
04/1995 - 04/1999	Laborleiter bioanalytisches Labor Pädiatrische Onkologie
07/1997 - 02/1998	PostDoc Pharmazeutische Industrie
Functions and Memberships
since 09/2005	Mitglied Arzneibuchkomission im Bundesinstitut für Arzneimittel und Medizinprodukte
10/2002 - 10/2008	Vorsitzender Fachgruppe Klinische Pharmazie in der DPhG
Appointments
06/2009	Offer to a Professorship for Klinische Pharmazie (W2) , Leipzig University

Publications

Anwendung stark wirksamer retardierter Opioide in der Pädiatrie : Fallstricke und Lösungen für Morphin und Hydromorphon Zimbelmann F, Flaute S, Deipenbrock M, Ahlke E, Hempel G, Baumann-Köhler M (2024) In: Schmerz, 204 Type of Publication: Research article (journal)
Development and validation of a bioanalytical method for the quantification of methotrexate from serum and capillary blood using volumetric absorptive microsampling (VAMS) and on… Opitz P, Fobker M, Fabian J, Hempel G (2024) In: Journal of Chromatographic Science, 1715 Type of Publication: Research article (journal)
Development and Validation of a High-Performance Liquid Chromatography With Ultraviolet Detection Method to Facilitate Therapeutic Monitoring of Teicoplanin Using Dried Blood Spots Ramadan, O.[1]; Opitz, P.[2,3]; Hempel, G. [4] (2024) In: Therapeutic Drug Monitoring, 00 Type of Publication: Research article (journal)
Systematic Evaluation of Pharmacokinetic Models for Model-Informed Precision Dosing of Meropenem in Critically Ill Patients Undergoing Continuous Renal Replacement Therapy. Schatz, LM; Brinkmann, A; Röhr, A; Frey, O; Greppmair, S; Weinelt, F; Zoller, M; Scharf, C; Hempel, G; Liebchen, U (2023) In: Antimicrobial Agents and Chemotherapy, 1 Type of Publication: Research article (journal)
Validation of a liquid chromatography-tandem mass spectrometry method for simultaneous quantification of N,N-dimethylacetamide and N-monomethylacetamide in pediatric plasma Rosser SPA, McLachlan AJ, Hempel G, Chung J, Shaw PJ, Keogh SJ, Nath CE (2023) In: Journal of Separation Science, 46(10) Type of Publication: Research article (journal)

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Projects

Erhöhung der Arzneimitteltherapiesicherheit durch digitales, interprofessionelles Medikationsmanagement - Digitales AMTS-Management Duration: 01/12/2019 - 30/11/2022 Funded by: Viandar GmbH Type of project: Individual project
ADMET/PBPK Model development of sexual hormone to evaluate toxicokinetics of endocrine disruptor Duration: 01/11/2019 - 31/12/2020 Funded by: Korea Institute of Science and Technology Type of project: Individual project
Bioanalytik eines FLT-3 Inhibitors Duration: 01/09/2019 - 30/11/2019 Funded by: Bayerische Patentallianz GmbH Type of project: Individual project
Entwicklung eines Instruments zur Messung der Effektivität pharmazeutischer Interventionen in Altenheimen Duration: 01/08/2019 - 31/01/2021 Funded by: Förderinitiative Pharmazeutische Betreuung e.V. Type of project: Individual project
Therapeutisches Drug Monitoring (TDM) von Antipsychotika und Antidepressiva mit getrockneten Kapillarblutproben im ambulanten Bereich Duration: 01/05/2019 - 30/10/2020 Funded by: Apothekerstiftung Westfalen-Lippe Type of project: Individual project

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Talks

Assessment of the Release of Daunorubicin from Liposomes after Administration of DaunoXome® using Population Pharmacokinetics. Liebich M, Robert J, Hempel G (13/09/2017) 2nd International Workshop on Clinical Pharmacology of Anticancer Drugs, Madrid, Spanien Type of talk: scientific talk
Modelling of Dexamethasone in Paediatric Leukaemia Patients using a Population Pharmacokinetic Approach Liebich M, Jackson RK, Irving JAE, Veal GJ, Hempel G (07/06/2017) 26th Population Approach Group in Europe Meeting, Budapest, Ungarn Type of talk: scientific talk
Modelling of Daunorubicin Release from Liposomes after Administration of DaunoXome® using a Population Pharmacokinetic Approach. Liebich M, Robert J, Hempel G (16/03/2017) 38th EORTC-PAMM Winter Meeting , Split, Kroatien Type of talk: scientific talk

Prizes

Posterpreis der Deutschen Gesellschaft für Klinische Pharmazie (DGKPha) Awarded by: Deutsche Gesellschaft für Klinische Pharmazie Award given to: Maierhöfer, Stefan; Waltering, Isabell;Würthwein, Gudrun;Hempel, Georg Announced at: 15/10/2021 \| Date of awarding: 15/10/2021 Type of distinction: Best publication award
Posterpreis DPhG 2018 (1. Platz) Klinische Pharmazie Awarded by: Deutsche Pharmazeutische Gesellschaft Award given to: Kneller L.A., Abad-Santos F., Hempel G. Announced at: 15/10/2018 \| Date of awarding: 15/10/2018 Type of distinction: Research award or other distinction
Dissertationspreis 2018 Awarded by: Paul-Ehrlich-Gesellschaft Wien Award given to: Gastine, Silke Elisabeth Announced at: 01/01/2018 \| Date of awarding: 01/01/2018 Type of distinction: Research award or other distinction
Best Practice Poster Awarded by: ADKA - Arbeitsgemeinschaft Deutscher Krankenhaus-Apotheker Award given to: Ilting-Reuke, Katharina; Hempel, Georg Date of awarding: 15/09/2017 Type of distinction: Best publication award
Gesundheitspreis NRW (2. Preis) Awarded by: Ministerium für Gesundheit und Soziales NRW Award given to: Hempel, Georg; Overwiening, Gabriele für die Apothekerkammer Westfalen-Lippe Date of awarding: 15/10/2013 Type of distinction: Research award or other distinction

Doctorates

Entwicklung einer Enzymsubstitutionstherapie bei Transglutaminase 1-defizienter lamellärer Ichthyose Candidate: Paul, Kris \| Supervisors: Langer, Klaus \| Reviewers: Langer, Klaus; Hempel, Georg Period of time: 01/04/2022 - 31/03/2025 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Bioanalytik von Rekombinanter Asparaginase und Physiologie-basierte Pharmakokinetik bei Kindern mit akuter lymphatischer Leukämie Candidate: Bauch, Thomas \| Supervisors: Hempel, Georg; Langer, Klaus Period of time: until 13/08/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Pathophysiologische Bedeutung von organischen Kationentransportern Candidate: Barz, Vivien \| Supervisors: Ciarimboli, Guiliano \| Reviewers: Hempel, Georg; Ciarimboli, Giuliano Period of time: 01/08/2018 - 01/07/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Precision dosing of risperidone and aripiprazole in the treatment of schizophrenia using a physiologically based pharmacokinetic approach: A focus on the… Candidate: Lisa Alina Kneller \| Supervisors: Hempel, Georg, Lehr Matthias Period of time: until 31/05/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Untersuchung physiologischer und pathophysiologischer Einflüsse auf die Heterogenität und den oxidativen Status von Mitochondrien der pankreatischen beta-Zelle Candidate: Beckmann, Dirk \| Supervisors: Düfer, Martina; Hempel, Georg; Esselen, Melanie Period of time: until 22/03/2021 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster

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