University of Münster
CRIS@UM
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Dr. rer. nat. Marc Hotfilder

Current affiliations

  • University Children's Hospital - Department of Paediatric Haematology and Oncology (UKM PHO)

Publications

ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution
de Faria, Flavia W.; Riedel, Nicole C.; Münter, Daniel; Interlandi, Marta; Göbel, Carolin; Altendorf, Lea; Richter, Mathis; Melcher, Viktoria; Thomas, Christian; Roy, Rajanya; Schoof, Melanie; Bedzhov, Ivan; Moreno, Natalia; Graf, Monika; Hotfilder, Marc; Holdhof, Dörthe; Hartmann, Wolfgang; Bruns, Ann-Katrin; Brentrup, Angela; Liesche-Starnecker, Friederike; Maerkl, Bruno; Sandmann, Sarah; Varghese, Julian; Dugas, Martin; Pinto, Pedro H.; Balbach, Sebastian T.;Lu, I-Na; Rossig, Claudia; Soehnlein, Oliver; Canak, Aysegül; Ebinger, Martin; Schuhmann, Martin; Schittenhelm, Jens; Frühwald, Michael F.; Schüller, Ulrich; Albert, Thomas K.; Walter, Carolin; Bruder, Jan M.; Kerl, Kornelius.  (2025)
In: Nature Communications, 16, 5394.
Research article (journal)
Group-specific cellular metabolism in Medulloblastoma
Funke V.L.E.; Walter C.; Melcher V.; Wei L.; Sandmann S.; Hotfilder M.; Varghese J.; Jäger N.; Kool M.; Jones D.T.W.; Pfister S.M.; Milde T.; Mynarek M.; Rutkowski S.; Seggewiss J.; Jeising D.; de Faria F.W.; Marquardt T.; Albert T.K.; Schüller U.; Kerl K. (2023)
In: Journal of Translational Medicine, 21(1).
Research article (journal)
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice
Brugmans A.K.; Walter C.; Moreno N.; Göbel C.; Holdhof D.; de Faria F.W.; Hotfilder M.; Jeising D.; Frühwald M.C.; Skryabin B.V.; Rozhdestvensky T.S.; Wachsmuth L.; Faber C.; Dugas M.; Varghese J.; Schüller U.; Albert T.K.; Kerl K. (2023)
In: Cellular and Molecular Neurobiology, 43(7).
Research article (journal)
Splice variants denote differences between a cancer stem cell side population of EWSR1.ERG.based Ewing sarcoma cells, its main population and EWSR1.FLI.based cells
Korsching, E; Matschke, J; Hotfilder, M (2022)
In: International Journal of Molecular Medicine, 49(3).
Research article (journal)
Defining a Characteristic Gene Expression Set Responsible for Cancer Stem Cell-Like Features in a Sub-Population of Ewing Sarcoma Cells CADO-ES1.
Hotfilder M, Mallela N, Seggewiß J, Dirksen U, Korsching E (2018)
In: International Journal of Molecular Sciences, 19.
Research article (journal)
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Projects

Funktionelle Analysen epigenetisch inaktivierter Kandidatengene in Hochrisikotumoren des ZNS von Kindern und Jugendlichen
Duration: 01/11/2010 - 31/10/2013
Funded by: Deutsche Krebshilfe e.V.
Type of project: Individual project
Translationales Sarkom-Netzwerk: TP 1.2 Promoter Methylierung und miRNA Expression bei Osteosarkomen und osteogenen Stammzellen, TP 1.3 Identifizierung und… (TRANSARNET)
Duration: 01/02/2009 - 31/05/2015
Funded by: Federal Ministry of Research, Technology and Space
Type of project: Participation in federally funded joint project
EWS/FLI-ChIP-on-Chip
Duration: 01/01/2009 - 31/12/2011
Funded by: Other public funder
Type of project: Individual project

Prizes

Kind-Philipp-Preis für pädiatrisch-onkologische Forschung 2008
Awarded by: Kind-Philipp-Stiftung für Leukämieforschung im Stifterverband für die Deutsche Wissenschaft
Award given to: Hotfilder, Dr. Marc; le Viseur, Christoph; Vormoor, Prof. Dr. Josef
Announced at: 15/05/2009 | Date of awarding: 15/05/2009
Type of distinction: Research award or other distinction