University of Münster
CRIS@UM
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Dr. rer. nat. Marc Hotfilder

Current affiliations

  • University Children's Hospital - Department of Paediatric Haematology and Oncology (UKM PHO)

Publications

Group-specific cellular metabolism in Medulloblastoma
Funke V.L.E.; Walter C.; Melcher V.; Wei L.; Sandmann S.; Hotfilder M.; Varghese J.; Jäger N.; Kool M.; Jones D.T.W.; Pfister S.M.; Milde T.; Mynarek M.; Rutkowski S.; Seggewiss J.; Jeising D.; de Faria F.W.; Marquardt T.; Albert T.K.; Schüller U.; Kerl K. (2023)
In: Journal of Translational Medicine, 21(1). doi:10.1186/s12967-023-04211-6
Research article (journal) | Peer reviewed | Published
Splice variants denote differences between a cancer stem cell side population of EWSR1.ERG.based Ewing sarcoma cells, its main population and EWSR1.FLI.based cells
Korsching, E; Matschke, J; Hotfilder, M (2022)
In: International Journal of Molecular Medicine, 49(3). doi:10.3892/ijmm.2022.5094
Research article (journal) | Peer reviewed | Published
Defining a Characteristic Gene Expression Set Responsible for Cancer Stem Cell-Like Features in a Sub-Population of Ewing Sarcoma Cells CADO-ES1.
Hotfilder M, Mallela N, Seggewiß J, Dirksen U, Korsching E (2018)
In: International Journal of Molecular Sciences, 19. doi:10.3390/ijms19123908
Research article (journal) | Peer reviewed | Published
The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting.
Kailayangiri S, Altvater B, Meltzer J, Pscherer S, Luecke A, Dierkes C, Titze U, Leuchte K, Landmeier S, Hotfilder M, Dirksen U, Hardes J, Gosheger G, Juergens H, Rossig C (2012)
In: British Journal of Cancer, 106(6), 1123-1133.
Research article (journal) | Peer reviewed | Published
GD2-SPECIFIC T CELLS EFFICIENTLY TARGET EWING SARCOMA CELLS IN VITRO AND IN VIVO
Kailayangiri S, Altvater B, Meltzer J, Pscherer S, Luecke A, Dierkes C, Leuchte K, Hotfilder M, Dirksen U, Hardes J, Gosheger G, Juergens H, Rossig C (2011)
In: Pediatric Blood and Cancer, 57(5), 710-711.
Research article (journal) | Published
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Projects

Funktionelle Analysen epigenetisch inaktivierter Kandidatengene in Hochrisikotumoren des ZNS von Kindern und Jugendlichen
Duration: 01/11/2010 - 31/10/2013
Funded by: Deutsche Krebshilfe e.V.
Type of project: Individual project
Translationales Sarkom-Netzwerk: TP 1.2 Promoter Methylierung und miRNA Expression bei Osteosarkomen und osteogenen Stammzellen, TP 1.3 Identifizierung und… (TRANSARNET)
Duration: 01/02/2009 - 31/05/2015
Funded by: Federal Ministry of Research, Technology and Space
Type of project: Participation in federally funded joint project
EWS/FLI-ChIP-on-Chip
Duration: 01/01/2009 - 31/12/2011
Funded by: Other public funder
Type of project: Individual project

Prizes

Kind-Philipp-Preis für pädiatrisch-onkologische Forschung 2008
Awarded by: Kind-Philipp-Stiftung für Leukämieforschung im Stifterverband für die Deutsche Wissenschaft
Award given to: Hotfilder, Dr. Marc; le Viseur, Christoph; Vormoor, Prof. Dr. Josef
Announced at: 15/05/2009 | Date of awarding: 15/05/2009
Type of distinction: Research award or other distinction