Prof. Dr. Thomas Pap
Current affiliations
- Institute of Musculoskeletal Medicine (IMM)
Curriculum Vitae (CV)
- Mesenchymal activation during chronic inflammation in joints and bone
- Cell-cell and cell-matrix interactions in fibroblast adhesion, migration and tissue invasion during arthritis
- Mechanisms of chondrocyte differentiation and chrondrocyte-mediated matrix remodelling under physiological, inflammatory and degenerative conditions
- Mechanisms of Bone remodelling and bone healing under chronic inflammatory conditions
Academic Education | |
| 2004 | Habilitation, Medical Faculty, University of Zürich |
| 1996 | Approbation |
| 1994 - 1996 | Resident, Department of Rheumatology, University of Magdeburg |
| 1995 | Medical degree 'Dr. med.', University of Magdeburg |
| 1994 | Praktisches Jahr (PJ) an der Medizinischen Fakultät der Otto-von-Guericke Universität Magdeburg (Innere Medizin, Chirurgie) sowie der Kantonalen Psychiatrischen Klinik St. Urban (Luzern, CH) (Psychiatrie) |
| 1988 - 1994 | Medical School, University of Magdeburg, (Graduation with 'Auszeichnung', Best Graduate Award) |
| 1991 | Elective period „National Rheumatology Centre“, Leeds, UK |
Work Experience | |
| since 2008 | Director of the Institute of Experimental Musculoskeletal Medicine, University of Münster |
| 2005 - 2008 | Professor of Experimental Medicine (tenure) and Head, Division of Molecular Medicine of Musculoskeletal Tissue, University Hospital Münster |
| 2001 - 2005 | Head of an ‘Emmy-Noether’ Group (funded by the German Research Foundation, DFG), University of Magdeburg |
| 2000 - 2004 | Head, Division of Experimental Rheumatology and Orthopaedics, Otto-von-Guericke University Magdeburg and Clinical Resident, Center for Internal Medicine |
| 1999 - 2000 | Senior Research Fellow, Center for Experimental Rheumatology and WHO Collaborating Center for Molecular Biology and Novel Therapeutic Strategies for Rheumatic Diseases, Department of Rheumatology, University Hospital Zurich |
| 1997 - 1999 | Postdoctoral Fellow, Center for Experimental Rheumatology and WHO Collaborating Center for Molecular Biology and Novel Therapeutic Strategies for Rheumatic Diseases, Department of Rheumatology, University Hospital Zurich |
Functions and Memberships | |
| since 2008 | International Journal of Rheumatology (Editorial board member) |
| since 2007 | Arthritis Research and Therapy (Editorial Board member) |
| since 2007 | Journal of Autoimmune Diseases (associate Editor deputy editor-in-chief) |
| since 2006 | Annals of the Rheumatid Diseases (Editorial Board member) |
| since 2006 | Rheumatology (Oxford) (Editorial Board member) |
| since 2006 | Clinical and Experimental Rheumatology (Editorial Board member) |
| since 2005 | Deputy member of the ethics commission - 'Ärztekammer Westfalen-Lippe' and medical Faculty, University of Münster (WWU) |
| since 2005 | Tutor of the German national academic foundation, University of Münster (WWU) |
| since 2002 | medactuell Rheumatologie (deputy editor-in-chief) |
| 2006 - 2007 | Associate Dean of the Faculty of Medicine, University of Münster (WWU) |
Publications
Stolberg-Stolberg, Josef; Boettcher, Annika; Sambale, Meike; Stuecker, Sina; Sherwood, Joanna; Raschke, Michael; Pap, Thomas; Bertrand, Jessica (2022) In: Cell Death and Disease, 13(3) Type of Publication: Research article (journal) | |
Klein S, Mentrup B, Timmen M, Sherwood J, Lindemann O, Fobker M, Kronenberg D, Pap T, Raschke MJ, Stange R (2020) In: Calcified Tissue International, Springer,, 106 Type of Publication: Research article (journal) | |
Severmann A-C, Jochmann K, Feller K, Bachvarova V, Piombo V, Holzer T, Brachvogel B, Stange R, Pap T, Esko J, Hoffmann D (2020) In: Osteoarthritis Cartilage, 28(7) Type of Publication: Research article (journal) | |
Stolberg-Stolberg Josef, Sambale Meike, Hansen Uwe, Schäfer Alexandra, Raschke Michael, Bertrand Jessica, Pap Thomas, Sherwood Joanna (2020) In: International Journal of Molecular Sciences (IJMS), 21(12) Type of Publication: Research article (journal) | |
Michel Philipp A., Kronenberg Daniel, Neu Gertje, Stolberg-Stolberg Josef, Frank Andre, Pap Thomas, Langer Martin, Fehr Michael, Raschke Michael J., Stange Richard (2020) In: Journal of Orthopaedic Translation, 24 Type of Publication: Research article (journal) |
Projects
Duration: 01/07/2016 - 30/06/2020 | 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster | |
Duration: 01/11/2012 - 31/10/2019 | 1st Funding period Funded by: DFG - Cluster of Excellence Type of project: Subproject in DFG-joint project hosted at University of Münster | |
Duration: 01/11/2012 - 31/12/2013 | 2nd Funding period Funded by: DFG - Individual Grants Programme Type of project: Individual project | |
Duration: 01/07/2012 - 30/06/2016 | 1st Funding period Funded by: DFG - Collaborative Research Centre Type of project: Subproject in DFG-joint project hosted at University of Münster | |
Duration: 01/02/2011 - 28/02/2014 Funded by: DFG - Individual Grants Programme Type of project: Individual project |
Talks
| Syndecan-1 deficient bone cells show an impaired molecular communication leading to alteration in callus remodeling during fracture healing Timmen Melanie, Hidding Heriburg, Pap Thomas, Götte Martin, Raschke Michael J., Stange Richard (05/03/2016) ORS 2016, Orlando, USA Type of talk: scientific talk | |
| Syndecan-1 deficient bone cells show an altered synthesis of bone cell communication molecules leading to decreased bone mass and altered fracture healing Melanie Timmen, Heriburg Hidding, Thomas Pap, Martin Götte, Michael J. Raschke, Richard Stange (12/06/2015) International Symposium on Bone Regeneration (ISBR), Julius Wolff Institut Charité, Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin Type of talk: scientific talk |
Prizes
| Posterpreis der DKOU Awarded by: Deutsche Gesellschaft für Orthopädie und Unfallchirurgie Award given to: Everding Jens, Kronenberg Daniel, Timmen Melanie, Wendler Louisa, Eckes Beate, Hansen Uwe, Pap Thomas, Raschke Michael J., Stange Richard Date of awarding: 15/10/2016 Type of distinction: Best publication award | |
| Pro Scientia-Förderpreis 2009 Awarded by: Eckhart-Buddecke-Stiftung zur Förderung der Medizinischen Grundlagenforschung Award given to: Sorokin, Lydia; Pap, Thomas; Bertrand, Jessica Date of awarding: 15/02/2010 Type of distinction: Best publication award | |
| Posterpreis 28th European Workshop for Rheumatology Research Awarded by: 28th European Workshop for Rheumatology Research, Toulouse, France Award given to: Timmen M, Echtermeyer F, Neugebauer K, Zwerina J, Schett G, Fuchs T, Raschke MJ, Pap T, Stange R Date of awarding: 01/01/2008 Type of distinction: Best publication award |
Doctorates
| Periprothetische Frakturen des proximalen Femurs: Ein biomechanischer Vergleich zweier winkelstabiler Plattensysteme zur Versorgung von Vancouver Typ-B1… Candidate: Schröder, Richard | Supervisors: Raschke, Michael J.; Pap, Thomas Period of time: until 16/11/2015 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| Molecular Mechanisms of Synovial Fibroblast Activation in Rheumatoid Arthritis Candidate: Frank, Svetlana | Supervisors: Pap, Thomas; Püschel, Andreas; Klämbt, Christian Period of time: 11/11/2008 - 30/04/2013 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| Die Rolle Sentrin spezifischer Proteasen in der stabilen Aktivierung von Synovialfibroblasten bei Patienten mit Rheumatoider Arthritis Candidate: Strietholt, Simon | Supervisors: Pap, Thomas; Püschel, Andreas; Liebau, Eva Period of time: 24/09/2007 - 15/02/2013 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| Entwicklung eines MR-kompatiblen Frakturmodells an der Ratte zum in vivo-Monitoring der Angiogenese im Verlauf der Frakturheilung
Candidate: Tiggemann, Hannah | Supervisors: Raschke, Michael J.; Pap, Thomas; Period of time: until 26/11/2012 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| Entwicklung eines in vitro Modells zur Quantifizierung der Degradation von knorpelspezifischen Kollagenfibrillen und Untersuchungen zum Degradationspotential… Candidate: Freyth, Katharina | Supervisors: Pap, Thomas; Paul, Rüdiger; Bruckner, Peter Period of time: 09/06/2008 - 01/10/2012 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster |