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Prof. Dr.rer.nat. et med. habil. Eberhard Korsching, PhD

Current affiliations

Academic profiles

Further Profiles

Curriculum Vitae (CV)

Research Focus

  • Cancer Biology
    The analysis of the complexity of the biological cell is a tricky adventure which exhibit a lot of analogies to other complex systems like the human society. Therefore research insights in biological systems might also inspire concepts in other sciences. We present here some of our activities, put them into a broader context and try to establish an archive of useful code snippets. The research effort is centred around the biological reaction networks and how they form this robust and adaptive cellular system. Besides this basic research efforts which rely on simulation studies and analysis of expression/ sequence data sets we apply these mechanistic insights to understand cancer formation and progression especially in breast and bone cancers. A minor focus deals with the definition of biological marker panels useful in diagnostics. http://complex-systems.uni-muenster.de
  • Cancer Progression
  • Bioinformatics and Computational Biology
  • Gene Regulation
  • Gene Expression
  • Genomics
  • Biological Networks
  • Regulation Mechanisms
  • Biostatistics
  • Next Generation Sequencing
  • Tissue Microarrays

Publications

A de novo assembly based fusion gene detection concept based on DNA-seq data of 100 Ewing sarcoma cases
Zhao X.; Hotfilder M.; Korsching E. (2026)
In: Briefings in Bioinformatics, 27(1). doi:10.1093/bib/bbag059
Research article (journal) | Peer reviewed | Published
Musashi inhibitor Ro 08-2750 attenuates triple-negative breast cancer cell proliferation and migration and acts as a novel chemo- and radiosensitizer
Brücksken, KA; Sicking, M; Korsching, E; Suárez-Arriaga, MC; Espinoza-Sánchez, NA; Marzi, A; Fuentes-Pananá, EM; Kemper, B; Götte, M; Eich, HT; Greve, B; Troschel, FM; (2025)
In: Biomedicine & Pharmacotherapy, 186, 118002. doi:10.1016/j.biopha.2025.118002
Research article (journal) | Peer reviewed | Published
Reduction in Musashi abundance results in cellular radiation sensitization through modification of various cellular pathways in triple-negative breast cancer
Sicking, Mark; Witten, Anika; Korsching, Eberhard; Eich, Hans Theodor; Greve, Burkhard; Troschel, Fabian (2025)
In: Strahlentherapie und Onkologie, 199.
Research article (journal) | Peer reviewed | Published
Evaluating the Effectiveness of Various Small RNA Alignment Techniques in Transcriptomic Analysis by Examining Different Sources of Variability Through a Multi-Alignment Approach
Zhao, X.; Korsching, E; (2025)
In: Biology Methods & Protocols, 8, 65. doi:10.3390/mps8030065
Research article (journal) | Peer reviewed | Published
Prognostic marker Musashi-2 modulates DNA damage response and radioresistance in diffuse large B-cell lymphoma.
Habig T; Reichstein L; Brücksken KA; Sicking M; Labisch J; Oertel M; Korsching E; Lenz G; Hailfinger S; Greve B; Troschel FM; Eich HT (2025)
In: Frontiers in cell and developmental biology, 13, 1575483-1575483. doi:10.3389/fcell.2025.1575483
Research article (journal) | Peer reviewed | Published
Show all publications (104)

Projects

PROspective VAlidation of Biomarkers in Ewing Sarcoma for personalised translational medicine (PROVABES)
Duration: 01/05/2013 - 30/04/2016
Funded by: Federal Ministry of Research, Technology and Space
Type of project: Participation in federally funded joint project
Translationales Sarkom-Netzwerk: TP 1.2 Promoter Methylierung und miRNA Expression bei Osteosarkomen und osteogenen Stammzellen, TP 1.3 Identifizierung und… (TRANSARNET)
Duration: 01/02/2009 - 31/05/2015
Funded by: Federal Ministry of Research, Technology and Space
Type of project: Participation in federally funded joint project
European network to promote research into uncommon cancers in adults and children: Pathology, Biology and Genetics of Bone Tumors (EuroBoNeT)
Duration: 01/02/2006 - 31/07/2011
Funded by: EC FP 6 - Networks of Excellence
Type of project: EU-project hosted outside University of Münster

Doctorates

Site specific gene expression patterns in oral cancer.
Candidate: Frohwitter, Gesche | Supervisors: Korsching Eberhard, Bürger Horst, Fillies Thomas
Period of time: 01/04/2016 - 31/08/2017
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Cytokeratin and protein expression patterns in squamous cell carcinoma of the oral cavity provide evidence for two distinct pathogenetic pathways
Candidate: Frohwitter, Gesche | Supervisors: Fillies, Thomas; Korsching, Eberhard
Period of time: 22/02/2012 - 04/04/2016
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
The pathogenesis of Osteosarcoma - systems biological approaches to explain cancer development and progression
Candidate: Poos, Kathrin | Supervisors: Korsching, Eberhard; Bornberg-Bauer, Erich
Period of time: 01/11/2009 - 01/02/2014
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Morphological and immunohistochemical analysis of progression pathways in invasive breast cancer
Candidate: Schymik, Barbara | Supervisors: Korsching, Eberhard; Bürger, Horst
Period of time: 01/04/2011 - 01/05/2013
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Evaluation of quality parameters for the brest cancer screening region Ostwestfalen
Candidate: Gräwingholt, Axel | Supervisors: Korsching, Eberhard; Bürger, Horst
Period of time: 01/06/2011 - 10/02/2012
Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Show all doctorates (8)