| Address: | Hüfferstrasse 1 48149 Münster Germany |
A fundamental link between genomes and ecosystems is represented by the availability of resources: genes and proteins are macromolecules constituted of atoms that are incorporated into the organisms via bio-geochemical cycles operating at the ecosystem level. Therefore, the availability of the different atomic building blocks of nucleotides and amino acids may in principle represent one of the forces shaping molecular evolution in natural ecosystems. Indeed, recent evidence suggests a pivotal, yet under-explored role of the availability of nitrogen and phosphorus, that are typically limiting in natural ecosystems and are fundamental components of nucleotides and amino acids. In this framework, our group focuses on a question of central importance in the integration of the evolutionary and ecosystem perspectives: the cost of resource acquisition from the environment and the consequences of such environmental limitations on the molecular architecture of the organisms. We integrate concepts and methods from molecular evolution and ecology to measure the strength of selection induced by nutrient constraints, and to determine the time scale on which this ecological factor is evolutionarily relevant.
Elser JJ, Acquisti C, Kumar S (2011) In: Trends in Ecology & Evolution, 26(1), 38-44. doi:10.1016/j.tree.2010.10.006 Research article (journal) | Published | |
He F, Chen WH, Collins S, Acquisti C, Goebel U, Ramos-Onsins S, Lercher MJ, de Meaux J (2010) In: Genetics, 185(2), 695-701. doi:10.1534/genetics.110.114629 Research article (journal) | Published | |
Acquisti C, Kumar S, Elser JJ (2009) In: Proceedings of the Royal Society B: Biological Sciences, 276(1667), 2605-2610. doi:10.1098/rspb.2008.1960 Research article (journal) | Published | |
Acquisti C, Elser JJ, Kumar S (2009) In: Molecular Biology and Evolution, 26(5), 953-6. doi:10.1093/molbev/msp038 Research article (journal) | Published | |
Collins S, de Meaux J, Acquisti C (2007) In: Genetics, 176(2), 1089-1099. doi:10.1534/genetics.107.072926 Research article (journal) | Published |
Duration: 01/01/2013 - 31/12/2018 Funded by: Santander Consumer Bank AG Type of project: Individual project | |
Molecular evolution in natural ecosystems: linking comparative genomics and biological stoichiometry Duration: 22/07/2010 - 21/07/2015 Funded by: Volkswagen Foundation - Evolutionary Biology Type of project: Individual project |
| The role of nutrient limitation in shaping genome composition in prokaryotes: an experimental evolution approach Candidate: Henze, Stefanie | Supervisors: Acquisti, Claudia Period of time: ??? Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| The impact of nitrogen deprivation on genome evolution in Escherichia coli Candidate: Henze, Stefanie | Supervisors: Acquisti, Claudia; Dobrindt, Ulrich Period of time: until 30/06/2016 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster | |
| On the evolution of complex genetic diseases Candidate: Preuss, Christoph | Supervisors: Stoll, Monika; Bornberg-Bauer, Erich; Acquisti, Claudia Period of time: 03/06/2008 - 16/12/2011 Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster |