Synthesis, activity, metabolic stability and cell permeability of new cytosolic phospholipase A2α inhibitors with 1-indolyl-3-phenoxypropan-2-one structure.

Subeska A; Voundi ME; Hanekamp W; Mulac D; Langer K; Lehr M (2023)

In: Bioorganic and Medicinal Chemistry Letters, 92.

Research article (journal)

Hexafluoroisopropyl carbamates as selective MAGL and dual MAGL/FAAH inhibitors: Biochemical and physicochemical properties.

Barth, M.; Rudolph, S.; Kampschulze, J.; Meyer zu Vilsendorf, I.; Hanekamp, W.; Mulac, D.; Langer, K.; Lehr, M. (2022)

In: ChemMedChem, 17.

Research article (journal)

Evaluation of inhibitors of the arachidonic acid cascade with intact platelets using an on-line dilution and on-line solid phase extraction HPLC-MS method

Fabian J, Mergemeier K, Lehr M (2021)

In: ((Bitte Journal prüfen)), 155.

Research article (journal)

Acylated 1H-1,2,4-triazol-5-amines targeting human coagulation factor XIIa and thrombin: Conventional and microscale synthesis, anticoagulant properties, and mechanism of action

Korff M, Imberg L, Will JM, Bückreiß N, Kalinina SA, Wenzel BM, Kastner GA, Daniliuc CG, Barth M, Ovsepyan RA, Butov KR, Humpf HU, Lehr M, Panteleev MA, Poso A, Karst U, Steinmetzer T, Bendas G, Kalinin DV. (2020)

In: Journal of Medicinal Chemistry, 63.

Research article (journal)

HPLC-UV assays for evaluation of inhibitors of mono and diamine oxidases using novel phenyltetrazolylalkanamine substrates

Mergemeier K, Lehr M (2018)

In: Analytical Biochemistry, 549.

Research article (journal)

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HPLC fluorescence assay for measuring the activity of NAPE-PLD and the action of inhibitors affecting this enzyme. Lange, Thomas; Depmeier, Tim; Strünker, Timo; Lehr, Matthias (2023) In: Journal of Pharmaceutical and Biomedical Analysis, 229. Research article (journal)
Synthesis, activity, metabolic stability and cell permeability of new cytosolic phospholipase A2α inhibitors with 1-indolyl-3-phenoxypropan-2-one structure. Subeska A; Voundi ME; Hanekamp W; Mulac D; Langer K; Lehr M (2023) In: Bioorganic and Medicinal Chemistry Letters, 92. Research article (journal)
Synthesis and pharmacokinetic properties of novel cPLA2α inhibitors with 1-(carboxyalkylpyrrolyl)-3-aryloxypropan-2-one structure. Subeska A; Althaus J; Hake T; Hanekamp W; Bettenworth D; Mulac D; Langer K; Lehr M (2023) In: Bioorganic & Medicinal Chemistry, 77. Research article (journal)
Hexafluoroisopropyl carbamates as selective MAGL and dual MAGL/FAAH inhibitors: Biochemical and physicochemical properties. Barth, M.; Rudolph, S.; Kampschulze, J.; Meyer zu Vilsendorf, I.; Hanekamp, W.; Mulac, D.; Langer, K.; Lehr, M. (2022) In: ChemMedChem, 17. Research article (journal)
High performance liquid chromatographic assays with UV-detection for evaluation of inhibitors of acetylcholinesterase and butyrylcholinesterase Michels G, Lehr M (2021) In: ((Bitte Journal prüfen)), 44. Research article (journal)
Evaluation of inhibitors of the arachidonic acid cascade with intact platelets using an on-line dilution and on-line solid phase extraction HPLC-MS method Fabian J, Mergemeier K, Lehr M (2021) In: ((Bitte Journal prüfen)), 155. Research article (journal)
Aryl N-[w-(6-fluoroindol-1-yl)alkyl]carbamates as inhibitors of fatty acid amide hydrolase, monoacylglycerol lipase and butyrylcholinesterase: Structure-activity relationships and hydrolytic stability Rudolph S, Dahlhaus H, Hanekamp W, Albers C, Barth M, Michels G, Friedrich D, Lehr M (2021) In: ACS Omega, 6. Research article (journal)
Acylated 1H-1,2,4-triazol-5-amines targeting human coagulation factor XIIa and thrombin: Conventional and microscale synthesis, anticoagulant properties, and mechanism of action Korff M, Imberg L, Will JM, Bückreiß N, Kalinina SA, Wenzel BM, Kastner GA, Daniliuc CG, Barth M, Ovsepyan RA, Butov KR, Humpf HU, Lehr M, Panteleev MA, Poso A, Karst U, Steinmetzer T, Bendas G, Kalinin DV. (2020) In: Journal of Medicinal Chemistry, 63. Research article (journal)
HPLC-UV assay for the evaluation of inhibitors of plasma amine oxidase using crude bovine plasma Mergemeier K, Galster F, Lehr M (2019) In: Journal of Enzyme Inhibition and Medicinal Chemistry, 34(144-149). Research article (journal)
HPLC-UV assays for evaluation of inhibitors of mono and diamine oxidases using novel phenyltetrazolylalkanamine substrates Mergemeier K, Lehr M (2018) In: Analytical Biochemistry, 549. Research article (journal)