Development and validation of a bioanalytical method for the quantification of methotrexate from serum and capillary blood using volumetric absorptive microsampling (VAMS) and on-line solid phase extraction (SPE) LC-MS.

Opitz P, Fobker M, Fabian J, Hempel G (2024)

In: Journal of Chromatographic Science, 1715, 464610. doi:10.1016/j.chroma.2023.464610

Research article (journal) | Peer reviewed | Published

Synthesis, activity, metabolic stability and cell permeability of new cytosolic phospholipase A2α inhibitors with 1-indolyl-3-phenoxypropan-2-one structure

Subeska, A; Voundi, M.E.; Hanekamp, W.; Mulac, D.; Langer, K.; Lehr, M. (2023)

In: Bioorganic and Medicinal Chemistry Letters, 92, 129374-129374. doi:10.1016/j.bmcl.2023.129374

Research article (journal) | Peer reviewed | Published

Hexafluoroisopropyl carbamates as selective MAGL and dual MAGL/FAAH inhibitors: Biochemical and physicochemical properties

Barth, M.; Rudolph, S.; Kampschulze, J.; Meyer zu Vilsendorf, I.; Hanekamp, W.; Mulac, D.; Langer, K.; Lehr, M. (2022)

In: ChemMedChem, 17, e2021007. doi:10.1002/cmdc.202100757

Research article (journal) | Peer reviewed | Published

Evaluation of inhibitors of the arachidonic acid cascade with intact platelets using an on-line dilution and on-line solid phase extraction HPLC-MS method

In: .

| Peer reviewed

Acylated 1H-1,2,4-triazol-5-amines targeting human coagulation factor XIIa and thrombin: Conventional and microscale synthesis, anticoagulant properties, and mechanism of action

In: , -.

| Peer reviewed

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Development and validation of a bioanalytical method for the quantification of methotrexate from serum and capillary blood using volumetric absorptive microsampling (VAMS) and on-line solid phase extraction (SPE) LC-MS. Opitz P, Fobker M, Fabian J, Hempel G (2024) In: Journal of Chromatographic Science, 1715, 464610. doi:10.1016/j.chroma.2023.464610 Research article (journal) \| Peer reviewed \| Published
HPLC fluorescence assay for measuring the activity of NAPE-PLD and the action of inhibitors affecting this enzyme. Lange, Thomas; Depmeier, Tim; Strünker, Timo; Lehr, Matthias (2023) In: Journal of Pharmaceutical and Biomedical Analysis, 229. doi:10.1016/j.jpba.2023.115354 Research article (journal) \| Peer reviewed \| Published
Synthesis, activity, metabolic stability and cell permeability of new cytosolic phospholipase A2α inhibitors with 1-indolyl-3-phenoxypropan-2-one structure Subeska, A; Voundi, M.E.; Hanekamp, W.; Mulac, D.; Langer, K.; Lehr, M. (2023) In: Bioorganic and Medicinal Chemistry Letters, 92, 129374-129374. doi:10.1016/j.bmcl.2023.129374 Research article (journal) \| Peer reviewed \| Published
Synthesis and pharmacokinetic properties of novel cPLA2α inhibitors with 1-(carboxyalkylpyrrolyl)-3-aryloxypropan-2-one structure Subeska, A.; Althaus, J.; Hake, T.; Hanekamp, W.; Bettenworth, D.; Mulac, D.; Langer, K.; Lehr, M. (2023) In: Bioorganic & Medicinal Chemistry, 77, 117110-117110. doi:10.1016/j.bmc.2022.117110 Research article (journal) \| Peer reviewed \| Published
Hexafluoroisopropyl carbamates as selective MAGL and dual MAGL/FAAH inhibitors: Biochemical and physicochemical properties Barth, M.; Rudolph, S.; Kampschulze, J.; Meyer zu Vilsendorf, I.; Hanekamp, W.; Mulac, D.; Langer, K.; Lehr, M. (2022) In: ChemMedChem, 17, e2021007. doi:10.1002/cmdc.202100757 Research article (journal) \| Peer reviewed \| Published
High performance liquid chromatographic assays with UV-detection for evaluation of inhibitors of acetylcholinesterase and butyrylcholinesterase In: . \| Peer reviewed
Evaluation of inhibitors of the arachidonic acid cascade with intact platelets using an on-line dilution and on-line solid phase extraction HPLC-MS method In: . \| Peer reviewed
Aryl N-[w-(6-fluoroindol-1-yl)alkyl]carbamates as inhibitors of fatty acid amide hydrolase, monoacylglycerol lipase and butyrylcholinesterase: Structure-activity relationships and hydrolytic stability In: , -. \| Peer reviewed
Acylated 1H-1,2,4-triazol-5-amines targeting human coagulation factor XIIa and thrombin: Conventional and microscale synthesis, anticoagulant properties, and mechanism of action In: , -. \| Peer reviewed
HPLC-UV assay for the evaluation of inhibitors of plasma amine oxidase using crude bovine plasma In: . \| Peer reviewed