University of Münster
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Role of the heparan sulfate sulfotransferase HS3ST2 in breast cancer cell motility and invasiveness

Basic data of the doctoral examination procedure

Doctoral examination procedure finished at: Doctoral examination procedure at University of Münster
Period of time: to 01/04/2011
Status: completed
Candidate: Gassar, Ezeddin Salem
Doctoral subject: Medizinische Wissenschaften
Doctoral degree: Dr. rer. medic.
Awarded by: Department 05 - Faculty of Medicine
Supervisors: Götte, Martin; Stock, Christian; Kiesel, Ludwig

Supervision at the University of Münster

Götte, Martin
Department of Gynecology and Obstetrics
Kiesel, Ludwig
Department of Gynecology and Obstetrics
Stock, Christian
Institute of Physiology II

Publications resulting from doctoral examination procedure

HS3ST2 modulates breast cancer cell invasiveness and chemosensitivity via MAP kinase- and TCF7L2/TCF4-dependent regulation of protease and cadherin expression
Kumar A, Gassar E, Spillmann D, Hulsewig C, Kiesel L, Stock C, Yip G, Gotte M (2014)
In: Oncology Research and Treatment, 37 1.
Research article (journal)
HS3ST2 modulates breast cancer cell invasiveness via MAP kinase-and Tcf4 (Tcf7l2)-dependent regulation of protease and cadherin expression
Kumar A., Gassar E., Spillmann D., Stock C., Sen Y., Zhang T., Van Kuppevelt T., Hulsewig C., Kozlowski E., Pavao M., Ibrahim S., Poeter M., Rescher U., Kiesel L., Koduru S., Yip G., Gotte M. (2014)
In: International Journal of Cancer, 135(11).
Research article (journal)
Heparan Sulfate Proteoglycans in Cancer Therapy
Salem Gassar E, Ibrahim SA, Götte M (2011)
In: Pavao MSG (eds.), Glycans in Diseases and Therapeutics. Berlin Heidelberg: Springer VDI Verlag.
Research article (book contribution)
Enoxaparin improves the course of dextran sodium sulfate-induced colitis in syndecan-1-deficient mice.
Floer M, Götte M, Wild MK, Heidemann J, Gassar ES, Domschke W, Kiesel L, Luegering A, Kucharzik T (2010)
In: American Journal of Pathology, 176(1).
Research article (journal)
An increase of 3-O-sulfation of Heparan sulfate by Overexpression of Sulfotransferases HS3ST2 brunt leads to MMP-Activity and strengthens Motility and Invasiveness of MDA-MB-231 Breast cancer cells.
Gotte M, Gassar E, Ibrahim S, Spillmann D, Yip G, Kiesel L (2010)
Other scientific publication