Dysphagia after stroke: research advances in treatment interventions.

Labeit B; Michou E; Trapl-Grundschober M; Suntrup-Krueger S; Muhle P; Bath PM; Dziewas R

Übersichtsartikel (Zeitschrift) | Peer reviewed

Zusammenfassung

After a stroke, most patients have dysphagia, which can lead to aspiration pneumonia, malnutrition, and adverse functional outcomes. Protective interventions aimed at reducing these complications remain the cornerstone of treatment. Dietary adjustments and oral hygiene help mitigate the risk of aspiration pneumonia, and nutritional supplementation, including tube feeding, might be needed to prevent malnutrition. Rehabilitative interventions aim to enhance swallowing function, with different behavioural strategies showing promise in small studies. Investigations have explored the use of pharmaceutical agents such as capsaicin and other Transient-Receptor-Potential-Vanilloid-1 (TRPV-1) sensory receptor agonists, which alter sensory perception in the pharynx. Neurostimulation techniques, such as transcranial direct current stimulation, repetitive transcranial magnetic stimulation, and pharyngeal electrical stimulation, might promote neuroplasticity within the sensorimotor swallowing network. Further advancements in the understanding of central and peripheral sensorimotor mechanisms in patients with dysphagia after a stroke, and during their recovery, will contribute to optimising treatment protocols.

Details zur Publikation

FachzeitschriftLancet Neurology (Lancet Neurol)
Jahrgang / Bandnr. / Volume23
Ausgabe / Heftnr. / Issue4
Seitenbereich418-428
StatusVeröffentlicht
Veröffentlichungsjahr2024 (01.05.2024)
Sprache, in der die Publikation verfasst istEnglisch
DOI10.1016/S1474-4422(24)00053-X
StichwörterHumans; Deglutition Disorders; Transcranial Direct Current Stimulation; Stroke; Stroke Rehabilitation; Pneumonia, Aspiration; Malnutrition

Autor*innen der Universität Münster

Suntrup-Krüger, Sonja
Klinik für Neurologie mit Institut für Translationale Neurologie