Frequency modulation stimulated Raman scattering scheme for real-time background correction with a single light source

Wallmeier, Kristin; Würthwein, Thomas; Lemberger, Nick; Brinkmann, Maximilian; Hellwig, Tim; Fallnich, Carsten

Forschungsartikel (Zeitschrift) | Peer reviewed

Zusammenfassung

A frequency modulation (FM) scheme for stimulated Raman scattering (SRS) is presented with a single fiber-based light source. Pulse-to-pulse wavelength-switching allows real-time subtraction of parasitic signals leaving only the resonant SRS signal with a noise reduction of up to 30 % compared to digital subtraction schemes, leading effectively to a contrast improvement by a factor of up to 8.3. The wide tuning range of the light source from 1500 cm−1 to 3000 cm−1 and the possibility to separately adjust the resonant and the nonresonant wavenumber for every specimen allow to investigate a variety of samples with high contrast and high signal-to-noise ratio, e. g., for medical diagnostics.

Details zur Publikation

FachzeitschriftBiomedical Optics Express
Jahrgang / Bandnr. / Volume14
Ausgabe / Heftnr. / Issue1
Seitenbereich315-325
StatusVeröffentlicht
Veröffentlichungsjahr2023
Sprache, in der die Publikation verfasst istEnglisch
DOI10.1364/BOE.476513
StichwörterStimulated Raman scattering; Contrast enhancement; Frequency modulation; Fiber-based light source

Autor*innen der Universität Münster

Brinkmann, Maximilian
Professur für Angewandte Physik (Prof. Fallnich)
Fallnich, Carsten
Professur für Angewandte Physik (Prof. Fallnich)
Hellwig, Tim
Professur für Angewandte Physik (Prof. Fallnich)
Lemberger, Nick Sidney
Professur für Angewandte Physik (Prof. Fallnich)
Wallmeier, Kristin
Professur für Angewandte Physik (Prof. Fallnich)
Würthwein, Thomas
Professur für Angewandte Physik (Prof. Fallnich)