Frequency modulation stimulated Raman scattering scheme for real-time background correction with a single light sourceOpen Access

Wallmeier, Kristin; Würthwein, Thomas; Lemberger, Nick; Brinkmann, Maximilian; Hellwig, Tim; Fallnich, Carsten

Forschungsartikel (Zeitschrift) | Peer reviewed

Zusammenfassung

A frequency modulation (FM) scheme for stimulated Raman scattering (SRS) is presented with a single fiber-based light source. Pulse-to-pulse wavelength-switching allows real-time subtraction of parasitic signals leaving only the resonant SRS signal with a noise reduction of up to 30 % compared to digital subtraction schemes, leading effectively to a contrast improvement by a factor of up to 8.3. The wide tuning range of the light source from 1500 cm−1 to 3000 cm−1 and the possibility to separately adjust the resonant and the nonresonant wavenumber for every specimen allow to investigate a variety of samples with high contrast and high signal-to-noise ratio, e. g., for medical diagnostics.

Details zur Publikation

FachzeitschriftBiomedical Optics Express
Jahrgang / Bandnr. / Volume14
Ausgabe / Heftnr. / Issue1
Seitenbereich315-325
StatusVeröffentlicht
Veröffentlichungsjahr2023
Sprache, in der die Publikation verfasst istEnglisch
StichwörterStimulated Raman scattering; Contrast enhancement; Frequency modulation; Fiber-based light source

Autor*innen der Universität Münster

Brinkmann, Maximilian
Fallnich, Carsten
Hellwig, Tim
Lemberger, Nick Sidney
Wallmeier, Kristin
Würthwein, Thomas