Primary Aneurysmal Bone Cyst and Its Recent Treatment Options: A Comparative Review of 74 Cases

Deventer N, Schulze M, Gosheger G, Vaal M, Deventer N

Forschungsartikel (Zeitschrift) | Peer reviewed

Zusammenfassung

(1) Background: An aneurysmal bone cyst (ABC) is a benign, locally aggressive tumor. Different treatment modalities are described in the literature i.e., en bloc resection, intralesional curettage and percutaneous sclerotherapy. (2) Methods: This single-center study is a review of 74 patients with primary ABCs who underwent a surgical treatment or polidocanol instillation. Cyst volume measurements using MRI and conventional radiographs are compared. (3) Results: The mean pre-interventional MRI-based cyst volume was 44.07 cm3 and the mean radiographic volume was 27.27 cm3. The recurrence rate after intralesional curettage with the need for further treatment was 38.2% (13/34). The instillation of polidocanol showed a significant reduction of the initial cyst volume (p < 0.001) but a persistent disease occurred in 29/32 cases (90.6%). In 10 of these 29 cases (34.5%) further treatment was necessary. After en bloc resection (eight cases) a local recurrence occurred in two cases (25%), in one case with the need for further treatment. (4) Conclusions: MRI scans are superior to biplanar radiographs in the examination of ABCs. Sequential percutaneous instillations of polidocanol are equally effective in the therapy of primary ABCs compared to intralesional curettage. However, several instillations have to be expected. In a considerable number of cases, a conversion to intralesional curettage or en bloc resection may be necessary.

Details zur Publikation

FachzeitschriftCancers
Jahrgang / Bandnr. / Volume13
Ausgabe / Heftnr. / Issue10
StatusVeröffentlicht
Veröffentlichungsjahr2021
Sprache, in der die Publikation verfasst istEnglisch
DOI10.3390/cancers13102362
Link zum Volltexthttps://www.mdpi.com/2072-6694/13/10/2362

Autor*innen der Universität Münster

Deventer, Niklas
Klinik für Allgemeine Orthopädie und Tumororthopädie
Deventer, Nils
Klinik für Kinder- und Jugendmedizin - Allgemeine Pädiatrie -
Gosheger, Georg
Klinik für Allgemeine Orthopädie und Tumororthopädie
Schulze, Martin
Klinik für Allgemeine Orthopädie und Tumororthopädie
Vaal, Marieke Mathilda
Klinik für Allgemeine Orthopädie und Tumororthopädie