PH-switchable ampholytic supramolecular copolymers

Frisch H., Unsleber J.P., Ludeker D., Peterlechner M., Brunklaus G., Waller M., Besenius P.

Zusammenfassung

β-sheet-encoded anionic and cationic dendritic peptide amphiphiles form supramolecular copolymers when self-assembled in a 1:1 feed ratio of the monomers. These ampholytic materials have been designed for on-off polymerization in response to pH triggers. The cooperative supramolecular self-assembly process is switched on at a physiologically relevant pHvalue and can be switched off by increasing or decreasing the pHvalue. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.