Survey of staphylococcal enterotoxin genes, exfoliative toxin genes, and toxic shock syndrome toxin 1 gene in non-Staphylococcus aureus species.
Becker K, Haverkämper G, von Eiff C, Roth R, Peters G
Forschungsartikel (Zeitschrift)Zusammenfassung
The aim of this study was to analyze the presence of staphylococcal exotoxin genes in staphylococci other than Staphylococcus aureus. Whereas for Staphylococcus aureus a large spectrum of different exotoxins responsible for toxin-mediated diseases has been described, only few and conflicting data are available regarding toxin production in all other staphylococcal species. A collection of clinical non-Staphylococcus aureus staphylococcal isolates were systematically screened for the presence of genes for toxic shock syndrome toxin 1, exfoliative toxins, and classical enterotoxins by using multiplex polymerase chain reaction enzyme immunoassays. In a total of 461 isolates of 18 different (sub)species derived from clinical specimens, no toxin gene sequences were amplified. The results indicate that the occurrence of toxin genes involved in staphylococcal toxin-mediated diseases is at least very rare in human-derived isolates of non-Staphylococcus aureus species.
Details zur Publikation
Autor*innen der Universität Münster
| Becker, Karsten | Institut für Medizinische Mikrobiologie |
Habilitationen, aus denen die Publikation resultiert
Enterotoxine, Exfoliativtoxine und Toxic-Shock-Syndrome-Toxin von Staphylokokken: Entwicklung und Einsatz von molekularbiologischen Verfahren zum Nachweis der… Habilitand*in: Becker, Karsten | Gutachter*innen: Prof. Dr. Georg PetersZeitraum: bis 05.02.2002 Habilitationsverfahren erfolgt(e) an: Habilitationsverfahren erfolgt(e) an der Universität Münster |