Single-cell profiling reveals preferential reduction of memory B cell subsets in cladribine patients that correlates with treatment response.

Teschner VE; Fleck AK; Walter C; Schwarze AS; Eschborn M; Wirth T; Steinberg OV; Schulte-Mecklenbeck A; Lu IN; Herrera-Rivero M; Janoschka C; Lünemann JD; Schwab N; Meyer Zu Hörste G; Varghese J; Gross CC; Pul R; Kleinschnitz C; Mader S; Meinl E; Stoll M; Wiendl H; Klotz L (2023)

In: Therapeutic Advances in Neurological Disorders, 16.

Forschungsartikel (Zeitschrift)

Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis

Herich S, Schneider-Hohendorf T, Rohlmann A, Khaleghi Ghadiri M, Schulte-Mecklenbeck A, Zondler L, Janoschka C, Ostkamp P, Richter J, Breuer J, Dimitrov S, Rammensee H, Grauer OM, Klotz L, Gross CC, Stummer W, Missler M, Zarbock A, Vestweber D, Wiendl H, Schwab N (2019)

In: Brain, 142(11).

Forschungsartikel (Zeitschrift)

Long-term natalizumab treatment enhances the pathogenic signature of Th17 cells - potential implications for treatment cessation?

Janoschka C, Schulte-Mecklenbeck A, Starost L, Schafflick D, Schneider-Hohendorf T, Hoerste GM, Gross CC, Schwab N, Kuhlmann T, Wiendl H, Klotz L (2018)

In: Multiple Sclerosis, 24(2).

Forschungsartikel (Zeitschrift)

Deep immune-profiling of monozygotic twins discordant for multiple sclerosis indicates that genetic identity overrides disease-specific immune features.

Gerdes LA, Janoschka C, Mannig B, Schulte-Mecklenbeck A, Gross CC, Eveslage M, Kuempfel T, Wiendl H, Hohlfeld R, Klotz L (2018)

In: Multiple Sclerosis, 24(2).

Forschungsartikel (Zeitschrift)

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Single-cell profiling reveals preferential reduction of memory B cell subsets in cladribine patients that correlates with treatment response. Teschner VE; Fleck AK; Walter C; Schwarze AS; Eschborn M; Wirth T; Steinberg OV; Schulte-Mecklenbeck A; Lu IN; Herrera-Rivero M; Janoschka C; Lünemann JD; Schwab N; Meyer Zu Hörste G; Varghese J; Gross CC; Pul R; Kleinschnitz C; Mader S; Meinl E; Stoll M; Wiendl H; Klotz L (2023) In: Therapeutic Advances in Neurological Disorders, 16. Forschungsartikel (Zeitschrift)
Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity Fleck AK, Hucke S, Teipel F, Eschborn M, Janoschka C, Liebmann M, Wami H, Korn L, Pickert G, Hartwig M, Wirth T, Herold M, Koch K, Falk-Paulsen M, Dobrindt U, Kovac S, Gross CC, Rosenstiel P, Trautmann M, Wiendl H, Schuppan D, Kuhlmann T, Klotz L (2021) In: Brain, 144(4). Forschungsartikel (Zeitschrift)
Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis Herich S, Schneider-Hohendorf T, Rohlmann A, Khaleghi Ghadiri M, Schulte-Mecklenbeck A, Zondler L, Janoschka C, Ostkamp P, Richter J, Breuer J, Dimitrov S, Rammensee H, Grauer OM, Klotz L, Gross CC, Stummer W, Missler M, Zarbock A, Vestweber D, Wiendl H, Schwab N (2019) In: Brain, 142(11). Forschungsartikel (Zeitschrift)
Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Populations into the Cerebrospinal Fluid-Results from the ToFingo Successor Study Lohmann L, Janoschka C, Schulte-Mecklenbeck A, Klinsing S, Kirstein L, Hanning U, Wirth T, Schneider-Hohendorf T, Schwab N, Gross CC, Eveslage M, Meuth SG, Wiendl H, Klotz L (2018) In: Frontiers in immunology, 9. Forschungsartikel (Zeitschrift)
Long-term natalizumab treatment enhances the pathogenic signature of Th17 cells - potential implications for treatment cessation? Janoschka C, Schulte-Mecklenbeck A, Starost L, Schafflick D, Schneider-Hohendorf T, Hoerste GM, Gross CC, Schwab N, Kuhlmann T, Wiendl H, Klotz L (2018) In: Multiple Sclerosis, 24(2). Forschungsartikel (Zeitschrift)
Dimethyl fumarate treatment alters T cell metabolism in multiple sclerosis Liebmann M, Janoschka C, Heimann A, Schulte-Mecklenbeck A, Schwab N, Gross CC, Meuth SG, Wiendl H, Klotz L (2018) In: Multiple Sclerosis, 24(2). Forschungsartikel (Zeitschrift)
Deep immune-profiling of monozygotic twins discordant for multiple sclerosis indicates that genetic identity overrides disease-specific immune features. Gerdes LA, Janoschka C, Mannig B, Schulte-Mecklenbeck A, Gross CC, Eveslage M, Kuempfel T, Wiendl H, Hohlfeld R, Klotz L (2018) In: Multiple Sclerosis, 24(2). Forschungsartikel (Zeitschrift)