Teriflunomide modulates antigen-specific immune responses in an affinity-dependent fashion by inhibiting T cell metabolism

Eschborn M, Klotz L, Lindner M, Liebmann M, Garrido BT, Breuer J, Herold M, Gross CC, Schulte-Mecklenbeck A, Hundehege P, Nebel G, Glander S, Campbell GR, Schneider-Hohendorf T, Eveslage M, Schwab N, Busch K, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H, Grp TS (2018)

In: Multiple Sclerosis, 24(2).

Research article (journal)

The bile acid receptor Farnesoid X receptor controls central nervous system autoimmunity via anti-inflammatory monocyte polarization inducing a distinct metabolic profile

Herold M, Bissmeier M, Fleck A-, Wiendl H, Klotz L (2018)

In: Multiple Sclerosis, 24(2).

Research article (journal)

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

Goebel K, Pankratz S, Asaridou C, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG (2016)

In: Nature Communications, 7.

Research article (journal)

The bile acid receptor FXR controls CNS autoimmunity in an IL-10-dependent fashion

Herold M, Hucke S, Liebmann M, Buck D, Luessi F, Meuth S, Zipp F, Hemmer B, Kuhlmann T, Wiendl H, Klotz L (2015)

In: Multiple Sclerosis, 21(11).

Research article (journal)

B7-H1 Selectively Controls T(H)17 Differentiation and Central Nervous System Autoimmunity via a Novel Non-PD-1-Mediated Pathway

Herold M, Posevitz V, Chudyka D, Hucke S, Gross C, Kurth F, Leder C, Loser K, Kurts C, Knolle P, Klotz L, Wiendl H (2015)

In: The Journal of Immunology, 195(8).

Research article (journal)

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Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity Fleck AK, Hucke S, Teipel F, Eschborn M, Janoschka C, Liebmann M, Wami H, Korn L, Pickert G, Hartwig M, Wirth T, Herold M, Koch K, Falk-Paulsen M, Dobrindt U, Kovac S, Gross CC, Rosenstiel P, Trautmann M, Wiendl H, Schuppan D, Kuhlmann T, Klotz L (2021) In: Brain, 144(4). Research article (journal)
Teriflunomide modulates antigen-specific immune responses in an affinity-dependent fashion by inhibiting T cell metabolism Eschborn M, Klotz L, Lindner M, Liebmann M, Garrido BT, Breuer J, Herold M, Gross CC, Schulte-Mecklenbeck A, Hundehege P, Nebel G, Glander S, Campbell GR, Schneider-Hohendorf T, Eveslage M, Schwab N, Busch K, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H, Grp TS (2018) In: Multiple Sclerosis, 24(2). Research article (journal)
Dietary supplementation with conjugated linoleic acid influences central nervous system autoimmunity via the gut-central nervous system axis Fleck A-, Hucke S, Hartwig M, Teipel F, Herold M, Berer K, Liebmann M, Kuzmanov I, Gruetzke B, Sagredos A, Eveslage M, Gross CC, Krishnamoorthy G, Dobrindt U, Schuppan D, Kuhlmann T, Wiendl H, Klotz L (2018) In: Multiple Sclerosis, 24(2). Research article (journal)
The bile acid receptor Farnesoid X receptor controls central nervous system autoimmunity via anti-inflammatory monocyte polarization inducing a distinct metabolic profile Herold M, Bissmeier M, Fleck A-, Wiendl H, Klotz L (2018) In: Multiple Sclerosis, 24(2). Research article (journal)
Repurposing multiple sclerosis drug dimethyl fumarate, a promising fast track candidate for systemic cutaneous T cell lymphoma treatment Herold M, Klotz L (2016) In: Translational Cancer Research, 5(7). Research article (journal)
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells Goebel K, Pankratz S, Asaridou C, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG (2016) In: Nature Communications, 7. Research article (journal)
Fingolimod treatment promotes regulatory phenotype and function of B cells Gruetzke B, Hucke S, Gross CC, Herold MVB, Posevitz-Fejfar A, Wildemann BT, Kieseier BC, Dehmel T, Wiendl H, Klotz L (2015) In: Annals of Clinical and Translational Neurology, 2(2). Research article (journal)
The bile acid receptor FXR controls CNS autoimmunity in an IL-10-dependent fashion Herold M, Hucke S, Liebmann M, Buck D, Luessi F, Meuth S, Zipp F, Hemmer B, Kuhlmann T, Wiendl H, Klotz L (2015) In: Multiple Sclerosis, 21(11). Research article (journal)
Delayed onset and reduced disease severity of spontaneous CNS autoimmunity by conjugated linoleic acid-rich diet Hucke S, Herold M, Hartwig M, Kuzmanov I, Gruetzke B, Eveslage M, Kuhlmann T, Wiendl H, Klotz L (2015) In: Multiple Sclerosis, 21(11). Research article (journal)
B7-H1 Selectively Controls T(H)17 Differentiation and Central Nervous System Autoimmunity via a Novel Non-PD-1-Mediated Pathway Herold M, Posevitz V, Chudyka D, Hucke S, Gross C, Kurth F, Leder C, Loser K, Kurts C, Knolle P, Klotz L, Wiendl H (2015) In: The Journal of Immunology, 195(8). Research article (journal)