From aggregation to activity: Developing a topical enzyme replacement therapy for a rare skin disease.

Paul, K.; Bodes, J.; Traupe, H.; Jose, J.; Langer, K. (2025)
In: Skin forum – Annual Meeting, Berlin, Germany.
Type of Publication: Poster

Development and characterization of recombinant LEKTI domain 8+9 for topical therapy in Netherton Syndrome.

Bodes, J.; Paul, K.; Süßmuth, K.; Traupe, H.; Langer, K. (2024)
In: DPhG Annual Meeting (2024), Münster, Germany.
Type of Publication: Poster

Long-term faithful recapitulation of transglutaminase 1-deficient lamellar ichthyosis in a skin-humanized mouse model, and insights from proteomic studies.

Aufenvenne K, Rice RH, Hausser I, Oji V, Hennies HC, Rio MD, Traupe H, Larcher F (2012)
In: Journal of Investigative Dermatology, 132(7)
Type of Publication: Research article (journal)

Mutations in the prostaglandin transporter SLCO2A1 cause primary hypertrophic osteoarthropathy with digital clubbing.

Busch J, Frank V, Bachmann N, Otsuka A, Oji V, Metze D, Shah K, Danda S, Watzer B, Traupe H, Bolz HJ, Kabashima K, Bergmann C (2012)
In: Journal of Investigative Dermatology, 132(10)
Type of Publication: Research article (journal)

Filaggrin deficiency in ichthyosis vulgaris (IV): increase of skin pH and evidence for imbalance of KLK activity in a 3D keratinocytic model for IV

Zaraeva I, Perusquia A, Tarinski T, Seller N, Aufenvenne K, Breitkreuz D, Hausser I, Traupe H, Oji V (2012)
In: Experimental Dermatology, 21(3)
Type of Publication: Research article (journal)

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Buffer screening for protein formulations: Early development of a topicalenzyme replacement therapy. Paul, K.; Bodes, J.; Traupe, H.; Jose, J.; Langer, K. (2025) In: 5th European Conference on Pharmaceutics, Porto, Portugal. Type of Publication: Poster
From aggregation to activity: Developing a topical enzyme replacement therapy for a rare skin disease. Paul, K.; Bodes, J.; Traupe, H.; Jose, J.; Langer, K. (2025) In: Skin forum – Annual Meeting, Berlin, Germany. Type of Publication: Poster
Improving the recombinant expression of a therapeutic skin protein utilizing fusion tags in E. coli. Paul, K.; Kohlmann, P.; Bodes, J.; Traupe, H.; Langer, K. (2024) In: DPhG Annual Meeting (2024), Münster, Germany. Type of Publication: Poster
Development and characterization of recombinant LEKTI domain 8+9 for topical therapy in Netherton Syndrome. Bodes, J.; Paul, K.; Süßmuth, K.; Traupe, H.; Langer, K. (2024) In: DPhG Annual Meeting (2024), Münster, Germany. Type of Publication: Poster
Response to dupilumab in two children with Netherton syndrome: Improvement of pruritus and scaling Sussmuth K, Traupe H, Loser K, Ständer S, Kessel C, Wittkowski H, Oji V (2021) In: Journal of the European Academy of Dermatology and Venereology, 35(2) Type of Publication: Research article (journal)
Long-term faithful recapitulation of transglutaminase 1-deficient lamellar ichthyosis in a skin-humanized mouse model, and insights from proteomic studies. Aufenvenne K, Rice RH, Hausser I, Oji V, Hennies HC, Rio MD, Traupe H, Larcher F (2012) In: Journal of Investigative Dermatology, 132(7) Type of Publication: Research article (journal)
Cystatin M/E knockdown by lentiviral delivery of shRNA impairs epidermal morphogenesis of human skin equivalents. Jansen PA, van den Bogaard EH, Kersten FF, Oostendorp C, van Vlijmen-Willems IM, Oji V, Traupe H, Hennies HC, Schalkwijk J, Zeeuwen PL (2012) In: Experimental Dermatology, 21(11) Type of Publication: Research article (journal)
Mutations in the prostaglandin transporter SLCO2A1 cause primary hypertrophic osteoarthropathy with digital clubbing. Busch J, Frank V, Bachmann N, Otsuka A, Oji V, Metze D, Shah K, Danda S, Watzer B, Traupe H, Bolz HJ, Kabashima K, Bergmann C (2012) In: Journal of Investigative Dermatology, 132(10) Type of Publication: Research article (journal)
Cystatin M/E knockdown by lentiviral delivery of shRNA impairs epidermal morphogenesis in a human skin equivalent Kersten F, Jansen P, van den Bogaard E, Oostendorp C, van Vlijmen-Willems I, Oji V, Traupe H, Hennies H, Schalkwijk J, Zeeuwen P (2012) In: Journal of Investigative Dermatology, 132 2 Type of Publication: Research article (journal)
Filaggrin deficiency in ichthyosis vulgaris (IV): increase of skin pH and evidence for imbalance of KLK activity in a 3D keratinocytic model for IV Zaraeva I, Perusquia A, Tarinski T, Seller N, Aufenvenne K, Breitkreuz D, Hausser I, Traupe H, Oji V (2012) In: Experimental Dermatology, 21(3) Type of Publication: Research article (journal)