Teriflunomide modulates antigen-specific immune responses in an affinity-dependent fashion by inhibiting T cell metabolism

Eschborn M, Klotz L, Lindner M, Liebmann M, Garrido BT, Breuer J, Herold M, Gross CC, Schulte-Mecklenbeck A, Hundehege P, Nebel G, Glander S, Campbell GR, Schneider-Hohendorf T, Eveslage M, Schwab N, Busch K, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H, Grp TS (2018)
In: Multiple Sclerosis, 24(2)
Type of Publication: Research article (journal)

PML risk stratification using anti-JCV antibody index and L-selectin

Schwab N, Schneider-Hohendorf T, Pignolet B, Spadaro M, Görlich D, Meinl I, Windhagen S, Tackenberg B, Breuer J, Cantó E, Kümpfel T, Hohlfeld R, Siffrin V, Luessi F, Posevitz-Fejfár A, Montalban X, Meuth SG, Zipp F, Gold R, Du Pasquier RA, Kleinschnitz C, Jacobi A, Comabella M, Bertolotto A, Brassat D, Wiendl H (2016)
In: Multiple Sclerosis Journal, 22(8)
Type of Publication: Research article (journal)

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

Goebel K, Pankratz S, Asaridou C, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG (2016)
In: Nature Communications, 7
Type of Publication: Research article (journal)

The two-pore domain K2P channel TASK2 drives human NK-cell proliferation and cytolytic function

Schulte-Mecklenbeck A, Bittner S, Ehling P, Doering F, Wischmeyer E, Breuer J, Herrmann AM, Wiendl H, Meuth SG, Gross CC (2015)
In: European Journal of Immunology, 45(9)
Type of Publication: Research article (journal)

VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells.

Schneider-Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, Gross CC, Flanagan K, Sorokin L, Vestweber D, Zarbock A, Schwab N, Wiendl H (2014)
In: Journal of Experimental Medicine, 211(9)
Type of Publication: Research article (journal)

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Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus Breuer J, Korpos E, Hannocks M, Schneider-Hohendorf T, Song J, Zondler L, Herich S, Flanagan K, Korn T, Zarbock A, Kuhlmann T, Sorokin L, Wiendl H, Schwab N (2018) In: Journal of Neuroinflammation, 15 Type of Publication: Research article (journal)
Teriflunomide modulates antigen-specific immune responses in an affinity-dependent fashion by inhibiting T cell metabolism Eschborn M, Klotz L, Lindner M, Liebmann M, Garrido BT, Breuer J, Herold M, Gross CC, Schulte-Mecklenbeck A, Hundehege P, Nebel G, Glander S, Campbell GR, Schneider-Hohendorf T, Eveslage M, Schwab N, Busch K, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H, Grp TS (2018) In: Multiple Sclerosis, 24(2) Type of Publication: Research article (journal)
Liver X receptor activation promotes differentiation of regulatory T cells Herold M, Breuer J, Hucke S, Knolle P, Schwab N, Wiendl H, Klotz L (2017) In: PloS one, 12(9) Type of Publication: Research article (journal)
PML risk stratification using anti-JCV antibody index and L-selectin Schwab N, Schneider-Hohendorf T, Pignolet B, Spadaro M, Görlich D, Meinl I, Windhagen S, Tackenberg B, Breuer J, Cantó E, Kümpfel T, Hohlfeld R, Siffrin V, Luessi F, Posevitz-Fejfár A, Montalban X, Meuth SG, Zipp F, Gold R, Du Pasquier RA, Kleinschnitz C, Jacobi A, Comabella M, Bertolotto A, Brassat D, Wiendl H (2016) In: Multiple Sclerosis Journal, 22(8) Type of Publication: Research article (journal)
CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing Schneider-Hohendorf T, Mohan H, Bien CG, Breuer J, Becker A, Goerlich D, Kuhlmann T, Widman G, Herich S, Elpers C, Melzer N, Dornmair K, Kurlemann G, Wiendl H, Schwab N (2016) In: Nature Communications, 7(null) Type of Publication: Research article (journal)
Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells Goebel K, Pankratz S, Asaridou C, Herrmann AM, Bittner S, Merker M, Ruck T, Glumm S, Langhauser F, Kraft P, Krug TF, Breuer J, Herold M, Gross CC, Beckmann D, Korb-Pap A, Schuhmann MK, Kuerten S, Mitroulis I, Ruppert C, Nolte MW, Panousis C, Klotz L, Kehrel B, Korn T, Langer HF, Pap T, Nieswandt B, Wiendl H, Chavakis T, Kleinschnitz C, Meuth SG (2016) In: Nature Communications, 7 Type of Publication: Research article (journal)
PML risk stratification using anti-JCV antibody index and L-selectin (CD62L) Schwab N, Schneider-Hohendorf T, Pignolet B, Spadaro M, Breuer J, Jacobi A, Comabella M, Bertolotto A, Brassat D, Wiendl H (2015) In: Neurology, 85(4) Type of Publication: Research article (journal)
The two-pore domain K2P channel TASK2 drives human NK-cell proliferation and cytolytic function Schulte-Mecklenbeck A, Bittner S, Ehling P, Doering F, Wischmeyer E, Breuer J, Herrmann AM, Wiendl H, Meuth SG, Gross CC (2015) In: European Journal of Immunology, 45(9) Type of Publication: Research article (journal)
Natalizumab treatment is associated with increased anti-JCV antibody seroconversion Schneider-Hohendorf T, Schwab N, Pignolet B, Breuer J, Brassat D, Wiendl H (2015) In: Multiple Sclerosis, 21(11) Type of Publication: Research article (journal)
VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells. Schneider-Hohendorf T, Rossaint J, Mohan H, Böning D, Breuer J, Kuhlmann T, Gross CC, Flanagan K, Sorokin L, Vestweber D, Zarbock A, Schwab N, Wiendl H (2014) In: Journal of Experimental Medicine, 211(9) Type of Publication: Research article (journal)