Single-cell profiling reveals preferential reduction of memory B cell subsets in cladribine patients that correlates with treatment response.

Teschner VE; Fleck AK; Walter C; Schwarze AS; Eschborn M; Wirth T; Steinberg OV; Schulte-Mecklenbeck A; Lu IN; Herrera-Rivero M; Janoschka C; Lünemann JD; Schwab N; Meyer Zu Hörste G; Varghese J; Gross CC; Pul R; Kleinschnitz C; Mader S; Meinl E; Stoll M; Wiendl H; Klotz L (2023)
In: Therapeutic Advances in Neurological Disorders, 16
Type of Publication: Research article (journal)

Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis

Herich S, Schneider-Hohendorf T, Rohlmann A, Khaleghi Ghadiri M, Schulte-Mecklenbeck A, Zondler L, Janoschka C, Ostkamp P, Richter J, Breuer J, Dimitrov S, Rammensee H, Grauer OM, Klotz L, Gross CC, Stummer W, Missler M, Zarbock A, Vestweber D, Wiendl H, Schwab N (2019)
In: Brain, 142(11)
Type of Publication: Research article (journal)

Long-term natalizumab treatment enhances the pathogenic signature of Th17 cells - potential implications for treatment cessation?

Janoschka C, Schulte-Mecklenbeck A, Starost L, Schafflick D, Schneider-Hohendorf T, Hoerste GM, Gross CC, Schwab N, Kuhlmann T, Wiendl H, Klotz L (2018)
In: Multiple Sclerosis, 24(2)
Type of Publication: Research article (journal)

Deep immune-profiling of monozygotic twins discordant for multiple sclerosis indicates that genetic identity overrides disease-specific immune features.

Gerdes LA, Janoschka C, Mannig B, Schulte-Mecklenbeck A, Gross CC, Eveslage M, Kuempfel T, Wiendl H, Hohlfeld R, Klotz L (2018)
In: Multiple Sclerosis, 24(2)
Type of Publication: Research article (journal)

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Single-cell profiling reveals preferential reduction of memory B cell subsets in cladribine patients that correlates with treatment response. Teschner VE; Fleck AK; Walter C; Schwarze AS; Eschborn M; Wirth T; Steinberg OV; Schulte-Mecklenbeck A; Lu IN; Herrera-Rivero M; Janoschka C; Lünemann JD; Schwab N; Meyer Zu Hörste G; Varghese J; Gross CC; Pul R; Kleinschnitz C; Mader S; Meinl E; Stoll M; Wiendl H; Klotz L (2023) In: Therapeutic Advances in Neurological Disorders, 16 Type of Publication: Research article (journal)
Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity Fleck AK, Hucke S, Teipel F, Eschborn M, Janoschka C, Liebmann M, Wami H, Korn L, Pickert G, Hartwig M, Wirth T, Herold M, Koch K, Falk-Paulsen M, Dobrindt U, Kovac S, Gross CC, Rosenstiel P, Trautmann M, Wiendl H, Schuppan D, Kuhlmann T, Klotz L (2021) In: Brain, 144(4) Type of Publication: Research article (journal)
Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis Herich S, Schneider-Hohendorf T, Rohlmann A, Khaleghi Ghadiri M, Schulte-Mecklenbeck A, Zondler L, Janoschka C, Ostkamp P, Richter J, Breuer J, Dimitrov S, Rammensee H, Grauer OM, Klotz L, Gross CC, Stummer W, Missler M, Zarbock A, Vestweber D, Wiendl H, Schwab N (2019) In: Brain, 142(11) Type of Publication: Research article (journal)
Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Populations… Lohmann L, Janoschka C, Schulte-Mecklenbeck A, Klinsing S, Kirstein L, Hanning U, Wirth T, Schneider-Hohendorf T, Schwab N, Gross CC, Eveslage M, Meuth SG, Wiendl H, Klotz L (2018) In: Frontiers in immunology, 9 Type of Publication: Research article (journal)
Long-term natalizumab treatment enhances the pathogenic signature of Th17 cells - potential implications for treatment cessation? Janoschka C, Schulte-Mecklenbeck A, Starost L, Schafflick D, Schneider-Hohendorf T, Hoerste GM, Gross CC, Schwab N, Kuhlmann T, Wiendl H, Klotz L (2018) In: Multiple Sclerosis, 24(2) Type of Publication: Research article (journal)
Dimethyl fumarate treatment alters T cell metabolism in multiple sclerosis Liebmann M, Janoschka C, Heimann A, Schulte-Mecklenbeck A, Schwab N, Gross CC, Meuth SG, Wiendl H, Klotz L (2018) In: Multiple Sclerosis, 24(2) Type of Publication: Research article (journal)
Deep immune-profiling of monozygotic twins discordant for multiple sclerosis indicates that genetic identity overrides disease-specific immune features. Gerdes LA, Janoschka C, Mannig B, Schulte-Mecklenbeck A, Gross CC, Eveslage M, Kuempfel T, Wiendl H, Hohlfeld R, Klotz L (2018) In: Multiple Sclerosis, 24(2) Type of Publication: Research article (journal)