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Consensus molecular subtyping of colorectal carcinoma brain metastases reveals a metabolic signature associated with poor patient survival Irmer B; Wlochowitz D; Krekeler C; Richter KM; Chandrabalan S; Bayerlova M; Wolff A; Lenz G; Conradi LC; Schildhaus HU; Stadelmann C; Rohde V; Proescholdt M; Salinas G; Homayounfar K; Kuhlmann T; Hailfinger S; Pukrop T; Menck K; Beissbarth T; Bleckmann A (2025) In: Molecular Oncology, 2025(1). Research article (journal)
Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound Janoschka C; Lindner M; Koppers N; Starost L; Liebmann M; Eschborn M; Schneider-Hohendorf T; Windener F; Schafflick D; Fleck AK; Koch K; Deffner M; Schwarze AS; Schulte-Mecklenbeck A; Metz I; Gross CC; Meuth SG; Schwab N; Meyer Zu Hörste G; Wiendl H; Kuhlmann T; Klotz L; Stoll M (2023) In: Proceedings of the National Academy of Sciences of the United States of America, 120(1). Research article (journal)
Stroke induces disease-specific myeloid cells in the brain parenchyma and pia. Beuker C, Schafflick D, Strecker JK, Heming M, Li X, Wolbert J, Schmidt-Pogoda A, Thomas C, Kuhlmann T, Aranda-Pardos I, A-Gonzalez N, Kumar PA, Werner Y, Kilic E, Hermann DM, Stumm R, Wiendl H, Minnerup J, Meyer Zu Hörste G (2022) In: Nature Communications, 13(1). Research article (journal)
Modulation of pacemaker channel function in a model of thalamocortical hyperexcitability by demyelination and cytokines. Chaudhary R, Albrecht S, Datunashvili M, Cerina M, Lüttjohann A, Han Y, Narayanan V, Chetkovich DM, Ruck T, Kuhlmann T, Pape HC, Meuth SG, Zobeiri M, Budde T (2022) In: Cerebral cortex, 32(20). Research article (journal)
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development Ruck T.; Bock S.; Pfeuffer S.; Schroeter C.B.; Cengiz D.; Marciniak P.; Lindner M.; Herrmann A.; Liebmann M.; Kovac S.; Gola L.; Rolfes L.; Pawlitzki M.; Opel N.; Hahn T.; Dannlowski U.; Pap T.; Luessi F.; Schreiber J.A.; Wünsch B.; Kuhlmann T.; Seebohm G.; Tackenberg B.; Seja P.; Döring F.; Wischmeyer E.; Chasan A.I.; Roth J.; Klotz L.; Meyer zu Hörste G.; Wiendl H.; Marschall T.; Floess S.; Huehn J.; Budde T.; Bopp T.; Bittner S.; Meuth S.G. (2022) In: Cell Research, 32(1). Research article (journal)
A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis. Ostkamp P; Deffner M; Schulte-Mecklenbeck A; Wünsch C; Lu IN; Wu GF; Goelz S; De Jager PL; Kuhlmann T; Gross CC; Klotz L; Meyer Zu Hörste G; Wiendl H; Schneider-Hohendorf T; Schwab N (2022) In: Science translational medicine, 14(673). Research article (journal)
CNS Pericytes Modulate Local T Cell Infiltration in EAE. Koch K; Lindner M; Fleck AK; Liebmann M; Eschborn M; Zondler L; Diéguez-Hurtado R; Adams RH; Meyer Zu Hörste G; Zarbock A; Kuhlmann T; Wiendl H; Klotz L (2022) In: International Journal of Molecular Sciences, 23(21). Research article (journal)
Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity Fleck AK, Hucke S, Teipel F, Eschborn M, Janoschka C, Liebmann M, Wami H, Korn L, Pickert G, Hartwig M, Wirth T, Herold M, Koch K, Falk-Paulsen M, Dobrindt U, Kovac S, Gross CC, Rosenstiel P, Trautmann M, Wiendl H, Schuppan D, Kuhlmann T, Klotz L (2021) In: Brain, 144(4). Research article (journal)
Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis Schafflick D, Xu CA, Hartlehnert M, Cole M, Schulte-Mecklenbeck A, Lautwein T, Wolbert J, Heming M, Meuth SG, Kuhlmann T, Gross CC, Wiendl H, Yosef N, Meyer Zu Horste G (2020) In: Nature Communications, 11(1). Research article (journal)
CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome Gross CC, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher AR, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud D, Loussouarn D, Parratt J, Barnett M, Buckland ME, Hardy TA, Reddel SW, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth SG, Martin-Blondel G, Wiendl H, Liblau R (2019) In: Nature Communications, 10(1). Research article (journal)