Optimizing the biodistribution of radiofluorinated barbiturate tracers for MMP imaging by introduction of fluorescent dyes as pharmacokinetic modulators

Schwegmann K, Hohn M, Hermann S, Schäfers M, Riemann B, Haufe G, Wagner S, Breyholz HJ (2020)
In: Bioconjugate Chemistry, 31(4)
Type of Publication: Research article (journal)

Syntheses of radioiodinated pyrimidine-2,4,6-triones as potential agents for non-invasive imaging of matrix metalloproteinases

Breyholz H., Kopka K., Schäfers M., Wagner S. (2017)
In: Pharmaceuticals, 10(2)
Type of Publication: Research article (journal)

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke.

Zinnhardt B, Viel T, Wachsmuth L, Vrachimis A, Wagner S, Breyholz H, Faust A, Hermann S, Kopka K, Faber C, Dollé F, Pappata S, Planas A, Tavitian B, Schäfers M, Sorokin L, Kuhlmann M, Jacobs A. (2015)
In: Journal of Cerebral Blood Flow and Metabolism, 35(11)
Type of Publication: Research article (journal)

A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation.

Hugenberg V, Breyholz HJ, Riemann B, Hermann S, Schober O, Schäfers M, Gangadharmath U, Mocharla V, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S (2012)
In: Journal of Medicinal Chemistry, 55(10)
Type of Publication: Research article (journal)

The MMP inhibitor (R)-2-(N-benzyl-4-(2-[(18)F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-methylbutanamide: Improved precursor synthesis and fully automated radiosynthesis.

Wagner S, Faust A, Breyholz HJ, Schober O, Schäfers M, Kopka K (2011)
In: Applied Radiation and Isotopes, 69(6)
Type of Publication: Research article (journal)

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Optimizing the biodistribution of radiofluorinated barbiturate tracers for MMP imaging by introduction of fluorescent dyes as pharmacokinetic modulators Schwegmann K, Hohn M, Hermann S, Schäfers M, Riemann B, Haufe G, Wagner S, Breyholz HJ (2020) In: Bioconjugate Chemistry, 31(4) Type of Publication: Research article (journal)
Synthesis and Preliminary In Vitro and In Vivo Evaluation of Thiirane‐Based Slow‐Binding MMP Inhibitors as Potential Radiotracers for PET Imaging Hohn M, Chang M, Meisel J E, Frost E, Schwegmann K, Hermann S, Schäfers M, Riemann B, Haufe G, Breyholz H-J, Wagner S (2018) In: Chemistryselect, 3(42) Type of Publication: Research article (journal)
Syntheses of radioiodinated pyrimidine-2,4,6-triones as potential agents for non-invasive imaging of matrix metalloproteinases Breyholz H., Kopka K., Schäfers M., Wagner S. (2017) In: Pharmaceuticals, 10(2) Type of Publication: Research article (journal)
Correlation of intraprostatic tumor extent with 68-Ga-PSMA distribution in patients with prostate cancer Rahbar K, Weckesser M, Huss S, Semjonow A, Breyholz HJ, Schrader AJ, Schaefers M, Boegemann M. (2016) In: J Nucl Med, 2016 Type of Publication: Research article (journal)
Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke. Zinnhardt B, Viel T, Wachsmuth L, Vrachimis A, Wagner S, Breyholz H, Faust A, Hermann S, Kopka K, Faber C, Dollé F, Pappata S, Planas A, Tavitian B, Schäfers M, Sorokin L, Kuhlmann M, Jacobs A. (2015) In: Journal of Cerebral Blood Flow and Metabolism, 35(11) Type of Publication: Research article (journal)
Efficient synthesis of a fluorine-18 labeled biotin derivative. Claesener M, Breyholz HJ, Hermann S, Faust A, Wagner S, Schober O, Schäfers M, Kopka K (2012) In: Nuclear Medicine and Biology, 39(8) Type of Publication: Research article (journal)
A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation. Hugenberg V, Breyholz HJ, Riemann B, Hermann S, Schober O, Schäfers M, Gangadharmath U, Mocharla V, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S (2012) In: Journal of Medicinal Chemistry, 55(10) Type of Publication: Research article (journal)
A New Generation of Radiofluorinated Pyrimidine-2,4,6-triones as MMP-Targeted Radiotracers for Positron Emission Tomography. Schrigten D, Breyholz HJ, Wagner S, Hermann S, Schober O, Schäfers M, Haufe G, Kopka K (2012) In: Journal of Medicinal Chemistry, 55(1) Type of Publication: Research article (journal)
The MMP inhibitor (R)-2-(N-benzyl-4-(2-[(18)F]fluoroethoxy)phenylsulphonamido)-N-hydroxy-3-methylbutanamide: Improved precursor synthesis and fully automated radiosynthesis. Wagner S, Faust A, Breyholz HJ, Schober O, Schäfers M, Kopka K (2011) In: Applied Radiation and Isotopes, 69(6) Type of Publication: Research article (journal)
Radiofluorinated pyrimidine-2,4,6-triones as molecular probes for noninvasive MMP-targeted imaging. Breyholz HJ, Wagner S, Faust A, Riemann B, Höltke C, Hermann S, Schober O, Schäfers M, Kopka K (2010) In: ChemMedChem, 5(5) Type of Publication: Research article (journal)