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Publications

The potassium channel K2P2.1 shapes the morphology and function of brain endothelial cells via actin network remodeling. Lichtenberg S, Vinnenberg L, Steffen F, Plegge I, Hanuscheck N, Dobelmann V, Gruchot J, Schroeter CB, Ramachandran H, Wasser B, Bachir D, Nelke C, Franz J, Riethmüller C, Tenzer S, Distler U, Vogelaar CF, Kusche-Vihrog K, Skryabin BV, Rozhdestvensky TS, Schwab A, Krutmann J, Rossi A, Budde T, Bittner S, Meuth SG, Ruck T. (2025) In: Nature Communications, 16(1), 6622. Research article (journal)
MMF induces antioxidative and anaplerotic pathways and is neuroprotective in hyperexcitability in vitro Gola, L; Bierhansl, L; Hummel, N; Korn, L; Pawlowski, M; Cerina, M; Hundehege, P; Budde, T; König, S; Meuth, S; Wiendl, H; Kovac, S (2023) In: Free Radical Biology and Medicine, 194. Research article (journal)
A novel NMDA receptor test model based on hiPSC-derived neural cells Disse P, Aymanns I, Ritter N, Peischard S, Korn L, Wiendl H, Pawlowski M, Kovac S, Meuth SG, Budde T, Strutz-Seebohm N, Wünsch B, Seebohm G (2023) In: Biological Chemistry, Ahead of Print. Research article (journal)
Imaging of KCa3.1 Channels in Tumor Cells with PET and Small-Molecule Fluorescent Probes Thale, I.; Maskri, S.; Grey, L.; Todesca, L. M.; Budde, T.; Maisuls, I.; Strassert; C. A.; Koch, O.; Schwab, A.; Wünsch, B. (2023) In: ChemMedChem, 18(2), e202200551. Research article (journal)
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination. Kapell H; Fazio L; Dyckow J; Schwarz S; Cruz-Herranz A; Mayer C; Campos J; D Este E; Möbius W; Cordano C; Pröbstel AK; Gharagozloo M; Zulji A; Narayanan Naik V; Delank AK; Müntefering T; Cerina M; Sonner JK; Lerma-Martin C; Disse P; Sin JH; Sabeur K; Rychlik N; Srivastava R; Chavali M; Fitzgerald KC; Heidenreich M; Stadelmann C; Seebohm G; Platten M; Hemmer B; Budde T; Nave KA; Jentsch TJ; Engelhardt M; Green AJ; Acuna C; Calabresi PA; Friese MA; Schirmer L; Rowitch DH; Meuth SG (2023) In: Journal of Clinical Investigation, Ahead of Print. Research article (journal)
Validation of TREK1 ion channel activators as an immunomodulatory and neuroprotective strategy in neuroinflammation. Schroeter CB; Nelke C; Schewe M; Spohler L; Herrmann AM; Müntefering T; Huntemann N; Kuzikov M; Gribbon P; Albrecht S; Bock S; Hundehege P; Neelsen LC; Baukrowitz T; Seebohm G; Bittner S; Wünsch B; Budde T; Ruck T; Meuth SG (2023) In: Biological Chemistry, Ahead of Print. Research article (journal)
Characterization of Kv1.2-mediated outward current in TRIP8b-deficient mice Afsaneh Labbaf, Maurice Dellin, Marlene Komadowski, Dane M. Chetkovich, Niels Decher, Hans-Chrisitian Pape, Guiscard Seebohm, Thomas Budde, Mehrnoush Zobeiri (2023) In: Biological Chemistry, 404(4). Research article (journal)
Optimized synthesis and pharmacological evaluation of HCN channel inhibitor EC18 Marius Patberg; Tengiz Oniani; Paul Disse; Stefan Peischard; Laura Vinnenberg; Mehrnoush Zobeiri; Maria N. Romanelli; Lisa Epping; Heinz Wiendl; Sven G. Meuth; Petra Hundehege; Guiscard Seebohm; Thomas Budde; Anna Junker (2023) In: Archiv der Pharmazie / Chemistry in Life Sciences, e2200665. Research article (journal)
Influence of inflammatory processes on thalamocortical activity Rychlik, Nicole; Hundehege, Petra; Budde, Thomas (2023) In: Biological Chemistry, 404(4). Review article (journal)
The second PI(3,5)P2 binding site in the S0 helix of KCNQ1 stabilizes PIP2-at the primary PI1 site with potential consequences on intermediate-to-open state transition. Dellin, Maurice; Rohrbeck, Ina; Asrani, Purva; Schreiber, Julian A; Ritter, Nadine; Glorius, Frank; Wünsch, Bernhard; Budde, Thomas; Temme, Louisa; Strünker, Timo; Stallmeyer, Birgit; Tüttelmann, Frank; Meuth, Sven G; Spehr, Marc; Matschke, Johann; Steinbicker, Andrea; Gatsogiannis, Christos; Stoll, Raphael; Strutz-Seebohm, Nathalie; Seebohm, Guiscard (2023) In: Journal of Biological Chemistry, 404(4). Research article (journal)