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Publications

Chemo-enzymatic production of base-modified ATP analogues for polyadenylation of RNA Mitton-Fry, Rachel M.; Eschenbach, Jannik; Schepers, Helena; Rasche, René; Erguven, Mehmet; Kümmel, Daniel; Rentmeister, Andrea; Cornelissen, Nicolas V. (2024) In: Chemical science, 15(32), 13068-13073. doi:10.1039/d4sc03769c Research article (journal) \| Peer reviewed \| Published
Engineered SAM synthetases for enzymatic generation of AdoMet analogs with photocaging groups and reversible DNA modification in cascade reactions Michailidou F, Klöcker N, Cornelissen NV, Singh RK, Peters A, Ovcharenko A, Kümmel D, Rentmeister A (2021) In: Angewandte Chemie International Edition, 60(1), 480-485. doi:10.1002/anie.202012623 Research article (journal) \| Peer reviewed \| Published
Biochemical and Structural Characterization of an Unusual and Naturally Split Class 3 Intein Hoffmann S, Terhorst TME, Singh RK, Kümmel D, Pietrokovski S, Mootz HD (2021) In: ((Bitte Journal prüfen)), 22(2), 364-373. doi:10.1002/cbic.202000509 Research article (journal) \| Peer reviewed \| Published
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, {Linard Matos} AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D (2021) In: Molecular Cell, 2021. doi:10.1016/j.molcel.2021.04.019 Research article (journal) \| Peer reviewed \| Published
Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations. Hansmann P, Brückner A, Kiontke S, Berkenfeld B, Seebohm G, Brouillard P, Vikkula M, Jansen FE, Nellist M, Oeckinghaus A, Kümmel D (2020) In: Structure, 28(8). doi:10.1016/j.str.2020.05.008 Research article (journal) \| Peer reviewed \| Published
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer. Escobar-Hoyos LF, Penson A, Kannan R, Cho H, Pan C, Singh RK, Apken LH, Hobbs GA, Luo R, Lecomte N, Babu S, Pan FC, Alonso-Curbelo D, Morris JP, Askan G, Grbovic-Huezo O, Ogrodowski P, Bermeo J, Saglimbeni J, Cruz CD, Ho Y, Lawrence SA, Melchor JP, Goda GA, Bai K, Pastore A, Hogg SJ, Raghavan S, Bailey P, Chang DK, Biankin A, Shroyer KR, Wolpin BM, Aguirre AJ, Ventura A, Taylor B, Der CJ, Dominguez D, Kümmel D, Oeckinghaus A, Lowe SW, Bradley RK, Abdel-Wahab O, Leach SD (2020) In: Cancer cell, 38(2). doi:10.1016/j.ccell.2020.05.010 Research article (journal) \| Peer reviewed \| Published
Comparison of the functional and structural characteristics of rare TSC2 variants with clinical and genetic findings {Dufner Almeida} LG, Nanhoe S, Zonta A, Hosseinzadeh M, Kom-Gortat R, Elfferich P, Schaaf G, Kenter A, Kümmel D, Migone N, Povey S, Ekong R, Nellist M (2020) In: Human Mutation, 41(4), 759-773. doi:10.1002/humu.23963 Research article (journal) \| Peer reviewed \| Published
Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction Lynagh T, Kiontke S, Meyhoff-Madsen M, Gless BH, Johannesen J, Kattelmann S, Christiansen A, Dufva M, Laustsen AH, Devkota K, Olsen CA, Kümmel D, Pless SA, Lohse B (2020) In: Journal of Medicinal Chemistry, 63(22), 13709-13718. doi:10.1021/acs.jmedchem.0c01202 Research article (journal) \| Peer reviewed \| Published
A conserved and regulated mechanism drives endosomal Rab transition Langemeyer L, Borchers A, Herrmann E, Füllbrunn N, Han Y, Perz A, Auffarth K, Kümmel D, Ungermann C (2020) In: eLife, 9. doi:10.7554/eLife.56090 Research article (journal) \| Peer reviewed \| Published
Structure of membrane tethers and their role in fusion Ungermann C, Kümmel D (2019) In: ((Bitte Journal prüfen)), 20(7), 479-490. doi:10.1111/tra.12655 Research article (journal) \| Peer reviewed \| Published