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Show 1 to 10 of 19 results

Chemo-enzymatic production of base-modified ATP analogues for polyadenylation of RNA Mitton-Fry, Rachel M.; Eschenbach, Jannik; Schepers, Helena; Rasche, René; Erguven, Mehmet; Kümmel, Daniel; Rentmeister, Andrea; Cornelissen, Nicolas V. (2024) In: Chemical science, 15(32), 13068-13073. doi:10.1039/d4sc03769c Research article (journal) \| Peer reviewed \| Published
Engineered SAM synthetases for enzymatic generation of AdoMet analogs with photocaging groups and reversible DNA modification in cascade reactions Michailidou F, Klöcker N, Cornelissen NV, Singh RK, Peters A, Ovcharenko A, Kümmel D, Rentmeister A (2021) In: Angewandte Chemie International Edition, 60(1), 480-485. doi:10.1002/anie.202012623 Research article (journal) \| Peer reviewed \| Published
Biochemical and Structural Characterization of an Unusual and Naturally Split Class 3 Intein Hoffmann S, Terhorst TME, Singh RK, Kümmel D, Pietrokovski S, Mootz HD (2021) In: ((Bitte Journal prüfen)), 22(2), 364-373. doi:10.1002/cbic.202000509 Research article (journal) \| Peer reviewed \| Published
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, {Linard Matos} AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D (2021) In: Molecular Cell, 2021. doi:10.1016/j.molcel.2021.04.019 Research article (journal) \| Peer reviewed \| Published
Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations. Hansmann P, Brückner A, Kiontke S, Berkenfeld B, Seebohm G, Brouillard P, Vikkula M, Jansen FE, Nellist M, Oeckinghaus A, Kümmel D (2020) In: Structure, 28(8). doi:10.1016/j.str.2020.05.008 Research article (journal) \| Peer reviewed \| Published
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer. In: . \| Peer reviewed
Comparison of the functional and structural characteristics of rare TSC2 variants with clinical and genetic findings In: , -. \| Peer reviewed
Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction In: , -. \| Peer reviewed
A conserved and regulated mechanism drives endosomal Rab transition In: . \| Peer reviewed
Structure of membrane tethers and their role in fusion In: , -. \| Peer reviewed

Escobar-Hoyos LF, Penson A, Kannan R, Cho H, Pan C, Singh RK, Apken LH, Hobbs GA, Luo R, Lecomte N, Babu S, Pan FC, Alonso-Curbelo D, Morris JP, Askan G, Grbovic-Huezo O, Ogrodowski P, Bermeo J, Saglimbeni J, Cruz CD, Ho Y, Lawrence SA, Melchor JP, Goda GA, Bai K, Pastore A, Hogg SJ, Raghavan S, Bailey P, Chang DK, Biankin A, Shroyer KR, Wolpin BM, Aguirre AJ, Ventura A, Taylor B, Der CJ, Dominguez D, Kümmel D, Oeckinghaus A, Lowe SW, Bradley RK, Abdel-Wahab O, Leach SD

(2020)

Cancer cell

, 38

(2)

doi:10.1016/j.ccell.2020.05.010

Research article (journal)

| Published

{Dufner Almeida} LG, Nanhoe S, Zonta A, Hosseinzadeh M, Kom-Gortat R, Elfferich P, Schaaf G, Kenter A, Kümmel D, Migone N, Povey S, Ekong R, Nellist M

(2020)

Human Mutation

, 41

(4)

759

773

doi:10.1002/humu.23963

Research article (journal)

| Published

Lynagh T, Kiontke S, Meyhoff-Madsen M, Gless BH, Johannesen J, Kattelmann S, Christiansen A, Dufva M, Laustsen AH, Devkota K, Olsen CA, Kümmel D, Pless SA, Lohse B

(2020)

Journal of Medicinal Chemistry

, 63

(22)

13709

13718

doi:10.1021/acs.jmedchem.0c01202

Research article (journal)

| Published

Langemeyer L, Borchers A, Herrmann E, Füllbrunn N, Han Y, Perz A, Auffarth K, Kümmel D, Ungermann C

(2020)

eLife

, 9

doi:10.7554/eLife.56090

Research article (journal)

| Published

Ungermann C, Kümmel D

(2019)

((Bitte Journal prüfen))

, 20

(7)

479

490

doi:10.1111/tra.12655

Research article (journal)

| Published

Chemo-enzymatic production of base-modified ATP analogues for polyadenylation of RNA Mitton-Fry, Rachel M.; Eschenbach, Jannik; Schepers, Helena; Rasche, René; Erguven, Mehmet; Kümmel, Daniel; Rentmeister, Andrea; Cornelissen, Nicolas V. (2024) In: Chemical science, 15(32), 13068-13073. doi:10.1039/d4sc03769c Research article (journal) \| Peer reviewed \| Published
Engineered SAM synthetases for enzymatic generation of AdoMet analogs with photocaging groups and reversible DNA modification in cascade reactions Michailidou F, Klöcker N, Cornelissen NV, Singh RK, Peters A, Ovcharenko A, Kümmel D, Rentmeister A (2021) In: Angewandte Chemie International Edition, 60(1), 480-485. doi:10.1002/anie.202012623 Research article (journal) \| Peer reviewed \| Published
Biochemical and Structural Characterization of an Unusual and Naturally Split Class 3 Intein Hoffmann S, Terhorst TME, Singh RK, Kümmel D, Pietrokovski S, Mootz HD (2021) In: ((Bitte Journal prüfen)), 22(2), 364-373. doi:10.1002/cbic.202000509 Research article (journal) \| Peer reviewed \| Published
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, {Linard Matos} AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D (2021) In: Molecular Cell, 2021. doi:10.1016/j.molcel.2021.04.019 Research article (journal) \| Peer reviewed \| Published
Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations. Hansmann P, Brückner A, Kiontke S, Berkenfeld B, Seebohm G, Brouillard P, Vikkula M, Jansen FE, Nellist M, Oeckinghaus A, Kümmel D (2020) In: Structure, 28(8). doi:10.1016/j.str.2020.05.008 Research article (journal) \| Peer reviewed \| Published
Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer. In: . \| Peer reviewed
Comparison of the functional and structural characteristics of rare TSC2 variants with clinical and genetic findings In: , -. \| Peer reviewed
Peptide Inhibitors of the α-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction In: , -. \| Peer reviewed
A conserved and regulated mechanism drives endosomal Rab transition In: . \| Peer reviewed
Structure of membrane tethers and their role in fusion In: , -. \| Peer reviewed