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Publications

ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution de Faria, Flavia W.; Riedel, Nicole C.; Münter, Daniel; Interlandi, Marta; Göbel, Carolin; Altendorf, Lea; Richter, Mathis; Melcher, Viktoria; Thomas, Christian; Roy, Rajanya; Schoof, Melanie; Bedzhov, Ivan; Moreno, Natalia; Graf, Monika; Hotfilder, Marc; Holdhof, Dörthe; Hartmann, Wolfgang; Bruns, Ann-Katrin; Brentrup, Angela; Liesche-Starnecker, Friederike; Maerkl, Bruno; Sandmann, Sarah; Varghese, Julian; Dugas, Martin; Pinto, Pedro H.; Balbach, Sebastian T.;Lu, I-Na; Rossig, Claudia; Soehnlein, Oliver; Canak, Aysegül; Ebinger, Martin; Schuhmann, Martin; Schittenhelm, Jens; Frühwald, Michael F.; Schüller, Ulrich; Albert, Thomas K.; Walter, Carolin; Bruder, Jan M.; Kerl, Kornelius. (2025) In: Nature Communications, 16, 5394. doi:10.1038/s41467-025-60442-9 Research article (journal) \| Peer reviewed \| Published
Determination of Fluconazole in Children in Small Blood Volumes Using Volumetric Absorptive Microsampling (VAMS) and Isocratic High-Performance Liquid Chromatography–Ultraviolet (HPLC–UV) Detection Zimbelmann F, Groll AH, Hempel G. (2025) In: Pharmaceutics, 17(5), 592. doi:10.3390/pharmaceutics17050592 Research article (journal) \| Peer reviewed \| Published
The potassium channel K2P2.1 shapes the morphology and function of brain endothelial cells via actin network remodeling. Lichtenberg S, Vinnenberg L, Steffen F, Plegge I, Hanuscheck N, Dobelmann V, Gruchot J, Schroeter CB, Ramachandran H, Wasser B, Bachir D, Nelke C, Franz J, Riethmüller C, Tenzer S, Distler U, Vogelaar CF, Kusche-Vihrog K, Skryabin BV, Rozhdestvensky TS, Schwab A, Krutmann J, Rossi A, Budde T, Bittner S, Meuth SG, Ruck T. (2025) In: Nature Communications, 16(1), 6622. doi:10.1038/s41467-025-61816-9 Research article (journal) \| Peer reviewed \| Published
The use of different microsampling tools for the determination of fluconazole from small blood volumes using HPLC-UV Zimbelmann, Franziska; Hempel, Georg;Groll, Andreas (2025) In: 7th International Caparica Christmas Conference on Sample Treatment, Costa da Caparica, Portugal. Poster \| Published
Anwendung stark wirksamer retardierter Opioide in der Pädiatrie : Fallstricke und Lösungen für Morphin und Hydromorphon Zimbelmann F, Flaute S, Deipenbrock M, Ahlke E, Hempel G, Baumann-Köhler M (2024) In: Der Schmerz, 204. doi:10.1007/s00482-023-00775-w Research article (journal) \| Peer reviewed \| Published
Preclinical Development of CAR T Cells with Antigen-Inducible IL18 Enforcement to Treat GD2-Positive Solid Cancers Fischer-Riepe, Lena; Kailayangiri, Sareetha; Zimmermann, Katharina; Pfeifer, Rita; Aigner, Michael; Altvater, Bianca; Kretschmann, Sascha; Voelkl, Simon; Hartley, Jordan; Dreger, Celine; Petry, Katja; Bosio, Andreas; von Doellen, Angelika; Hartmann, Wolfgang; Lode, Holger; Goerlich, Dennis; Mackensen, Andreas; Jungblut, Melanie; Schambach, Axel; Abken, Hinrich; Rossig, Claudia (2024) In: Clinical Cancer Research, 30(16), 3564-3577. doi:10.1158/1078-0432.CCR-23-3157 Research article (journal) \| Peer reviewed \| Published
MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas Sigaud R.; Albert T.K.; Hess C.; Hielscher T.; Winkler N.; Kocher D.; Walter C.; Münter D.; Selt F.; Usta D.; Ecker J.; Brentrup A.; Hasselblatt M.; Thomas C.; Varghese J.; Capper D.; Thomale U.W.; Hernáiz Driever P.; Simon M.; Horn S.; Herz N.A.; Koch A.; Sahm F.; Hamelmann S.; Faria-Andrade A.; Jabado N.; Schuhmann M.U.; Schouten-van Meeteren A.Y.N.; Hoving E.; Brummer T.; van Tilburg C.M.; Pfister S.M.; Witt O.; Jones D.T.W.; Kerl K.; Milde T. (2023) In: Nature Communications, 14(1). doi:10.1038/s41467-023-40235-8 Research article (journal) \| Peer reviewed \| Published
Mitochondrial DNA mutations in Medulloblastoma Funke V.L.E.; Sandmann S.; Melcher V.; Seggewiss J.; Horvath J.; Jäger N.; Kool M.; Jones D.T.W.; Pfister S.M.; Milde T.; Rutkowski S.; Mynarek M.; Varghese J.; Sträter R.; Rust S.; Seelhöfer A.; Reunert J.; Fiedler B.; Schüller U.; Marquardt T.; Kerl K. (2023) In: Acta neuropathologica communications, 11(1). doi:10.1186/s40478-023-01602-0 Research article (journal) \| Peer reviewed \| Published
Group-specific cellular metabolism in Medulloblastoma Funke V.L.E.; Walter C.; Melcher V.; Wei L.; Sandmann S.; Hotfilder M.; Varghese J.; Jäger N.; Kool M.; Jones D.T.W.; Pfister S.M.; Milde T.; Mynarek M.; Rutkowski S.; Seggewiss J.; Jeising D.; de Faria F.W.; Marquardt T.; Albert T.K.; Schüller U.; Kerl K. (2023) In: Journal of Translational Medicine, 21(1). doi:10.1186/s12967-023-04211-6 Research article (journal) \| Peer reviewed \| Published
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice Brugmans A.K.; Walter C.; Moreno N.; Göbel C.; Holdhof D.; de Faria F.W.; Hotfilder M.; Jeising D.; Frühwald M.C.; Skryabin B.V.; Rozhdestvensky T.S.; Wachsmuth L.; Faber C.; Dugas M.; Varghese J.; Schüller U.; Albert T.K.; Kerl K. (2023) In: Cellular and Molecular Neurobiology, 43(7), 3511-3526. doi:10.1007/s10571-023-01361-5 Research article (journal) \| Peer reviewed \| Published